Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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121 genes differentially expressed following the BRD-K88510285_B675700.cdx_DV90_6.0_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABHD4 | abhydrolase domain containing 4 |
ADGRG2 | adhesion G protein-coupled receptor G2 |
ANXA1 | annexin A1 |
ARG2 | arginase 2 |
ARMCX1 | armadillo repeat containing, X-linked 1 |
ARMCX3 | armadillo repeat containing, X-linked 3 |
ARMCX6 | armadillo repeat containing, X-linked 6 |
ATF3 | activating transcription factor 3 |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
BAG3 | BCL2-associated athanogene 3 |
CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
COL6A3 | collagen, type VI, alpha 3 |
CSTA | cystatin A (stefin A) |
DMXL1 | Dmx-like 1 |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
DPP4 | dipeptidyl-peptidase 4 |
EDNRB | endothelin receptor type B |
FOLR1 | folate receptor 1 (adult) |
GLRX | glutaredoxin (thioltransferase) |
GREB1 | growth regulation by estrogen in breast cancer 1 |
GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
HMOX1 | heme oxygenase 1 |
HSPA1A | heat shock 70kDa protein 1A |
HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
HSPA8 | heat shock 70kDa protein 8 |
HSPB8 | heat shock 22kDa protein 8 |
HSPD1 | heat shock 60kDa protein 1 (chaperonin) |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
KLF4 | Kruppel-like factor 4 (gut) |
MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
MEF2C | myocyte enhancer factor 2C |
MFAP3L | microfibrillar-associated protein 3-like |
MIR22HG | MIR22 host gene |
MME | membrane metallo-endopeptidase |
MPO | myeloperoxidase |
MSMB | microseminoprotein, beta- |
NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
NKX3-1 | NK3 homeobox 1 |
NQO2 | NAD(P)H dehydrogenase, quinone 2 |
PEG3 | paternally expressed 3 |
PIR | pirin (iron-binding nuclear protein) |
PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
PRPF4B | pre-mRNA processing factor 4B |
PSAP | prosaposin |
PTPRM | protein tyrosine phosphatase, receptor type, M |
RGS1 | regulator of G-protein signaling 1 |
SCGB2A1 | secretoglobin, family 2A, member 1 |
SGK1 | serum/glucocorticoid regulated kinase 1 |
TBPL1 | TBP-like 1 |
TBX3 | T-box 3 |
TENM1 | teneurin transmembrane protein 1 |
TFPI2 | tissue factor pathway inhibitor 2 |
TMEM47 | transmembrane protein 47 |
TMSB15A | thymosin beta 15a |
TUBB2A | tubulin, beta 2A class IIa |
WARS | tryptophanyl-tRNA synthetase |
WASL | Wiskott-Aldrich syndrome-like |
Symbol | Name |
---|---|
ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 |
AMPD3 | adenosine monophosphate deaminase 3 |
APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
B3GNT1 | |
CA12 | carbonic anhydrase XII |
CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
CCL20 | chemokine (C-C motif) ligand 20 |
CD24 | CD24 molecule |
CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
CFB | complement factor B |
CPA3 | carboxypeptidase A3 (mast cell) |
CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
CXCL14 | chemokine (C-X-C motif) ligand 14 |
DHCR24 | 24-dehydrocholesterol reductase |
EPHB2 | EPH receptor B2 |
ERBB2 | erb-b2 receptor tyrosine kinase 2 |
EREG | epiregulin |
ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
FAM57A | family with sequence similarity 57, member A |
FGB | fibrinogen beta chain |
FTO | fat mass and obesity associated |
GLUL | glutamate-ammonia ligase |
GPRC5A | G protein-coupled receptor, class C, group 5, member A |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
IFITM1 | interferon induced transmembrane protein 1 |
IFITM2 | interferon induced transmembrane protein 2 |
IGHD | immunoglobulin heavy constant delta |
IGL | immunoglobulin lambda locus |
IL32 | interleukin 32 |
IPO13 | importin 13 |
LAPTM4B | lysosomal protein transmembrane 4 beta |
LCN2 | lipocalin 2 |
LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
MFSD10 | major facilitator superfamily domain containing 10 |
MMD | monocyte to macrophage differentiation-associated |
MMP7 | matrix metallopeptidase 7 |
MT1E | metallothionein 1E |
MYB | v-myb avian myeloblastosis viral oncogene homolog |
NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
PDZK1IP1 | PDZK1 interacting protein 1 |
PI3 | peptidase inhibitor 3, skin-derived |
PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
PON2 | paraoxonase 2 |
PRSS3 | protease, serine, 3 |
RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
RNF43 | ring finger protein 43 |
S100A9 | S100 calcium binding protein A9 |
SCARB1 | scavenger receptor class B, member 1 |
SEPP1 | selenoprotein P, plasma, 1 |
SIRT3 | sirtuin 3 |
SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
TMEM45A | transmembrane protein 45A |
TNS3 | tensin 3 |
TPSAB1 | tryptase alpha/beta 1 |
TPSB2 | tryptase beta 2 (gene/pseudogene) |
ZFP36L2 | ZFP36 ring finger protein-like 2 |