Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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95 genes differentially expressed following the BRD-K88510285_B675700.cdx_HCC515_6.0_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ASNS | asparagine synthetase (glutamine-hydrolyzing) |
ATF3 | activating transcription factor 3 |
BAG3 | BCL2-associated athanogene 3 |
BHLHE41 | basic helix-loop-helix family, member e41 |
CEMIP | cell migration inducing protein, hyaluronan binding |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
CLC | Charcot-Leyden crystal galectin |
DEFA4 | defensin, alpha 4, corticostatin |
DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
ESR1 | estrogen receptor 1 |
HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
HMOX1 | heme oxygenase 1 |
HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
HSPA1A | heat shock 70kDa protein 1A |
HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
HSPA8 | heat shock 70kDa protein 8 |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
LTF | lactotransferrin |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
NEFH | neurofilament, heavy polypeptide |
NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
NRIP1 | nuclear receptor interacting protein 1 |
NRIP3 | nuclear receptor interacting protein 3 |
PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SOD2 | superoxide dismutase 2, mitochondrial |
STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 |
SV2C | synaptic vesicle glycoprotein 2C |
TAC1 | tachykinin, precursor 1 |
USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) |
Symbol | Name |
---|---|
ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
ALDH9A1 | aldehyde dehydrogenase 9 family, member A1 |
ANXA3 | annexin A3 |
ASPH | aspartate beta-hydroxylase |
AXL | AXL receptor tyrosine kinase |
C2CD5 | C2 calcium-dependent domain containing 5 |
C7 | complement component 7 |
CAV1 | caveolin 1, caveolae protein, 22kDa |
CCND1 | cyclin D1 |
CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
CTSC | cathepsin C |
DUSP6 | dual specificity phosphatase 6 |
EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
EPCAM | epithelial cell adhesion molecule |
ERLIN1 | ER lipid raft associated 1 |
FAM57A | family with sequence similarity 57, member A |
FHL1 | four and a half LIM domains 1 |
GRB14 | growth factor receptor-bound protein 14 |
GSTM3 | glutathione S-transferase mu 3 (brain) |
HES1 | hes family bHLH transcription factor 1 |
IFITM1 | interferon induced transmembrane protein 1 |
IFITM3 | interferon induced transmembrane protein 3 |
IGFBP3 | insulin-like growth factor binding protein 3 |
KRT18 | keratin 18, type I |
KRT8 | keratin 8, type II |
LAMB1 | laminin, beta 1 |
LAMC1 | laminin, gamma 1 (formerly LAMB2) |
MARCKSL1 | MARCKS-like 1 |
MGP | matrix Gla protein |
NBEA | neurobeachin |
NES | nestin |
NFIB | nuclear factor I/B |
PCGF2 | polycomb group ring finger 2 |
PEG10 | paternally expressed 10 |
PLA2G16 | phospholipase A2, group XVI |
PRKCB | protein kinase C, beta |
PTGIS | prostaglandin I2 (prostacyclin) synthase |
PXDN | peroxidasin |
RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
RBPMS | RNA binding protein with multiple splicing |
SFRP1 | secreted frizzled-related protein 1 |
SOX4 | SRY (sex determining region Y)-box 4 |
SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
SRPX | sushi-repeat containing protein, X-linked |
ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
SYNM | synemin, intermediate filament protein |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
TIMP1 | TIMP metallopeptidase inhibitor 1 |
TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
TPM1 | tropomyosin 1 (alpha) |
TPM2 | tropomyosin 2 (beta) |
TSPAN8 | tetraspanin 8 |
XIST | X inactive specific transcript (non-protein coding) |