| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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153 genes differentially expressed following the BRD-K88510285_B675700.cdx_JHUEM2_6.0_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADAM10 | ADAM metallopeptidase domain 10 |
| ADM | adrenomedullin |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| BAG3 | BCL2-associated athanogene 3 |
| BTG2 | BTG family, member 2 |
| C3 | complement component 3 |
| CADM1 | cell adhesion molecule 1 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| CD44 | CD44 molecule (Indian blood group) |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CPB1 | carboxypeptidase B1 (tissue) |
| CPE | carboxypeptidase E |
| CRISP3 | cysteine-rich secretory protein 3 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DENND1B | DENN/MADD domain containing 1B |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| EVI2A | ecotropic viral integration site 2A |
| FILIP1L | filamin A interacting protein 1-like |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GDF15 | growth differentiation factor 15 |
| GRB7 | growth factor receptor-bound protein 7 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HMOX1 | heme oxygenase 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IFI16 | interferon, gamma-inducible protein 16 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL32 | interleukin 32 |
| IPO13 | importin 13 |
| ITM2C | integral membrane protein 2C |
| JUN | jun proto-oncogene |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LRMP | lymphoid-restricted membrane protein |
| LYZ | lysozyme |
| MAP7 | microtubule-associated protein 7 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MYRF | myelin regulatory factor |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OSER1 | oxidative stress responsive serine-rich 1 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 |
| PLK2 | polo-like kinase 2 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| RGCC | regulator of cell cycle |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SIK1 | salt-inducible kinase 1 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLC38A1 | solute carrier family 38, member 1 |
| SLC38A2 | solute carrier family 38, member 2 |
| SNX13 | sorting nexin 13 |
| SULF1 | sulfatase 1 |
| SYNJ2 | synaptojanin 2 |
| TES | testin LIM domain protein |
| THBS1 | thrombospondin 1 |
| TPD52L1 | tumor protein D52-like 1 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| TXNL4B | thioredoxin-like 4B |
| UFD1L | ubiquitin fusion degradation 1 like (yeast) |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VEGFA | vascular endothelial growth factor A |
| WARS | tryptophanyl-tRNA synthetase |
| WT1 | Wilms tumor 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZFPM2 | zinc finger protein, FOG family member 2 |
| Symbol | Name |
|---|---|
| ACOT9 | acyl-CoA thioesterase 9 |
| ADRA2A | adrenoceptor alpha 2A |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| CA12 | carbonic anhydrase XII |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CCND1 | cyclin D1 |
| CCNF | cyclin F |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CDC42 | cell division cycle 42 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 |
| CHRDL1 | chordin-like 1 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| CYB5A | cytochrome b5 type A (microsomal) |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DEFB1 | defensin, beta 1 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EFNB2 | ephrin-B2 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FOLR1 | folate receptor 1 (adult) |
| FSTL1 | follistatin-like 1 |
| GPX3 | glutathione peroxidase 3 |
| GSTA4 | glutathione S-transferase alpha 4 |
| HAT1 | histone acetyltransferase 1 |
| HN1 | hematological and neurological expressed 1 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
| KLK11 | kallikrein-related peptidase 11 |
| KRT10 | keratin 10, type I |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| LEPR | leptin receptor |
| LPL | lipoprotein lipase |
| LYPLA1 | lysophospholipase I |
| MAGED1 | melanoma antigen family D1 |
| MLEC | malectin |
| MSX1 | msh homeobox 1 |
| NFIB | nuclear factor I/B |
| NUP62 | nucleoporin 62kDa |
| PLAGL1 | pleiomorphic adenoma gene-like 1 |
| PLK1 | polo-like kinase 1 |
| PNMA1 | paraneoplastic Ma antigen 1 |
| PRAF2 | PRA1 domain family, member 2 |
| PRDX4 | peroxiredoxin 4 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 |
| PUF60 | poly-U binding splicing factor 60KDa |
| RPL27A | ribosomal protein L27a |
| RPL38 | ribosomal protein L38 |
| RPS11 | ribosomal protein S11 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| S100A7 | S100 calcium binding protein A7 |
| SEPHS1 | selenophosphate synthetase 1 |
| SET | SET nuclear proto-oncogene |
| SETBP1 | SET binding protein 1 |
| SFN | stratifin |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 |
| SLIRP | SRA stem-loop interacting RNA binding protein |
| SLIT2 | slit homolog 2 (Drosophila) |
| SLPI | secretory leukocyte peptidase inhibitor |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
| SRPX | sushi-repeat containing protein, X-linked |
| TFF3 | trefoil factor 3 (intestinal) |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TGFBR3 | transforming growth factor, beta receptor III |
| TLR4 | toll-like receptor 4 |
| TSPAN3 | tetraspanin 3 |
| TYRP1 | tyrosinase-related protein 1 |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| ZNF586 | zinc finger protein 586 |
