| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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147 genes differentially expressed following the BRD-K88510285_B675700.cdx_NCIH596_6.0_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ATF3 | activating transcription factor 3 |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| C3 | complement component 3 |
| CA2 | carbonic anhydrase II |
| CALML3 | calmodulin-like 3 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CLDND1 | claudin domain containing 1 |
| CPB1 | carboxypeptidase B1 (tissue) |
| CPE | carboxypeptidase E |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CSRP1 | cysteine and glycine-rich protein 1 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DENND1B | DENN/MADD domain containing 1B |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| FAM129A | family with sequence similarity 129, member A |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GAGE3 | G antigen 3 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HOXB2 | homeobox B2 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HYOU1 | hypoxia up-regulated 1 |
| IER3 | immediate early response 3 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL32 | interleukin 32 |
| IPO13 | importin 13 |
| JCHAIN | joining chain of multimeric IgA and IgM |
| JUN | jun proto-oncogene |
| KDM6A | lysine (K)-specific demethylase 6A |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MBTPS1 | membrane-bound transcription factor peptidase, site 1 |
| MMP2 | matrix metallopeptidase 2 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| PEG10 | paternally expressed 10 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PMM2 | phosphomannomutase 2 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 |
| RGCC | regulator of cell cycle |
| SERINC5 | serine incorporator 5 |
| SFRP4 | secreted frizzled-related protein 4 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SHB | Src homology 2 domain containing adaptor protein B |
| SMC1A | structural maintenance of chromosomes 1A |
| SOCS1 | suppressor of cytokine signaling 1 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| TMEM176B | transmembrane protein 176B |
| TMSB15A | thymosin beta 15a |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| TRIB3 | tribbles pseudokinase 3 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| WSB1 | WD repeat and SOCS box containing 1 |
| XBP1 | X-box binding protein 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ALOX5 | arachidonate 5-lipoxygenase |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| BEX1 | brain expressed, X-linked 1 |
| CCDC85B | coiled-coil domain containing 85B |
| CCND1 | cyclin D1 |
| CD24 | CD24 molecule |
| CDC25B | cell division cycle 25B |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CHPT1 | choline phosphotransferase 1 |
| CSTB | cystatin B (stefin B) |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| EDNRB | endothelin receptor type B |
| EGR3 | early growth response 3 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| EIF5A | eukaryotic translation initiation factor 5A |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FAM57A | family with sequence similarity 57, member A |
| FBXO21 | F-box protein 21 |
| FZD7 | frizzled class receptor 7 |
| GMDS | GDP-mannose 4,6-dehydratase |
| GPX2 | glutathione peroxidase 2 |
| GPX3 | glutathione peroxidase 3 |
| HOXA10 | homeobox A10 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IRS2 | insulin receptor substrate 2 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KDM5D | lysine (K)-specific demethylase 5D |
| MAB21L2 | mab-21-like 2 (C. elegans) |
| MAMLD1 | mastermind-like domain containing 1 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MRPS2 | mitochondrial ribosomal protein S2 |
| NEBL | nebulette |
| NFIB | nuclear factor I/B |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NPY | neuropeptide Y |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NRN1 | neuritin 1 |
| OLFM1 | olfactomedin 1 |
| PAX5 | paired box 5 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PEBP1 | phosphatidylethanolamine binding protein 1 |
| PRKCZ | protein kinase C, zeta |
| PROM1 | prominin 1 |
| PRR7 | proline rich 7 (synaptic) |
| PRSS23 | protease, serine, 23 |
| PTGES | prostaglandin E synthase |
| PXMP2 | peroxisomal membrane protein 2, 22kDa |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RPS11 | ribosomal protein S11 |
| S100P | S100 calcium binding protein P |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SFN | stratifin |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SORD | sorbitol dehydrogenase |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| STOM | stomatin |
| TACC2 | transforming, acidic coiled-coil containing protein 2 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TESC | tescalcin |
| TLR4 | toll-like receptor 4 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TSPAN4 | tetraspanin 4 |
| TSPAN8 | tetraspanin 8 |
| UPK1B | uroplakin 1B |
