| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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130 genes differentially expressed following the BRD-K88510285_B675700.cdx_SKMEL1_6.0_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 |
| ACTB | actin, beta |
| BAG3 | BCL2-associated athanogene 3 |
| CA12 | carbonic anhydrase XII |
| CALB1 | calbindin 1, 28kDa |
| CLDN10 | claudin 10 |
| CLTB | clathrin, light chain B |
| CLTC | clathrin, heavy chain (Hc) |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 |
| E2F2 | E2F transcription factor 2 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FBLN5 | fibulin 5 |
| FKBP5 | FK506 binding protein 5 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) |
| HMOX1 | heme oxygenase 1 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| KLK11 | kallikrein-related peptidase 11 |
| KNG1 | kininogen 1 |
| LRRC17 | leucine rich repeat containing 17 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MFSD10 | major facilitator superfamily domain containing 10 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| PLEC | plectin |
| PXMP2 | peroxisomal membrane protein 2, 22kDa |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SFRP4 | secreted frizzled-related protein 4 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TFF3 | trefoil factor 3 (intestinal) |
| TPD52L1 | tumor protein D52-like 1 |
| TSPAN8 | tetraspanin 8 |
| TUBA4A | tubulin, alpha 4a |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ADAMDEC1 | ADAM-like, decysin 1 |
| ADGRF5 | adhesion G protein-coupled receptor F5 |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ATP9A | ATPase, class II, type 9A |
| AURKA | aurora kinase A |
| AUTS2 | autism susceptibility candidate 2 |
| BEX1 | brain expressed, X-linked 1 |
| C3ORF14 | chromosome 3 open reading frame 14 |
| CALD1 | caldesmon 1 |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CD24 | CD24 molecule |
| CD69 | CD69 molecule |
| CDC20 | cell division cycle 20 |
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CPE | carboxypeptidase E |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
| CTSS | cathepsin S |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DARS | aspartyl-tRNA synthetase |
| DPT | dermatopontin |
| EFNB2 | ephrin-B2 |
| EFS | embryonal Fyn-associated substrate |
| FST | follistatin |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| INTS6 | integrator complex subunit 6 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KLHL9 | kelch-like family member 9 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MEF2C | myocyte enhancer factor 2C |
| MEIS1 | Meis homeobox 1 |
| MMP9 | matrix metallopeptidase 9 |
| MXRA7 | matrix-remodelling associated 7 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NPTX2 | neuronal pentraxin II |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NTS | neurotensin |
| NXN | nucleoredoxin |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| PTTG1 | pituitary tumor-transforming 1 |
| RBPMS | RNA binding protein with multiple splicing |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RGS1 | regulator of G-protein signaling 1 |
| RGS5 | regulator of G-protein signaling 5 |
| RIN2 | Ras and Rab interactor 2 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SOX11 | SRY (sex determining region Y)-box 11 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SULF1 | sulfatase 1 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) |
| TMEM47 | transmembrane protein 47 |
| TMEM5 | transmembrane protein 5 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| TRIB2 | tribbles pseudokinase 2 |
| ZNF395 | zinc finger protein 395 |
