| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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169 genes differentially expressed following the BRD-K88510285_B675700.cdx_T3M10_6.0_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| BAG3 | BCL2-associated athanogene 3 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| CLEC2B | C-type lectin domain family 2, member B |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| FA2H | fatty acid 2-hydroxylase |
| FASTKD5 | FAST kinase domains 5 |
| FZD6 | frizzled class receptor 6 |
| GDF15 | growth differentiation factor 15 |
| GPM6B | glycoprotein M6B |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMOX1 | heme oxygenase 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IER5 | immediate early response 5 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI44L | interferon-induced protein 44-like |
| IGF1R | insulin-like growth factor 1 receptor |
| IL17RB | interleukin 17 receptor B |
| IL6 | interleukin 6 |
| IRF7 | interferon regulatory factor 7 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat |
| KCTD5 | potassium channel tetramerization domain containing 5 |
| KRT6A | keratin 6A, type II |
| LCN2 | lipocalin 2 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MECOM | MDS1 and EVI1 complex locus |
| MMP10 | matrix metallopeptidase 10 |
| NDRG1 | N-myc downstream regulated 1 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NRIP1 | nuclear receptor interacting protein 1 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) |
| PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTN | pleiotrophin |
| RANBP9 | RAN binding protein 9 |
| RGS1 | regulator of G-protein signaling 1 |
| RPS11 | ribosomal protein S11 |
| S100A9 | S100 calcium binding protein A9 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SPRR1A | small proline-rich protein 1A |
| SPRR1B | small proline-rich protein 1B |
| SPRR3 | small proline-rich protein 3 |
| SRGN | serglycin |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 |
| TMEM41B | transmembrane protein 41B |
| TMEM97 | transmembrane protein 97 |
| UBE3C | ubiquitin protein ligase E3C |
| WSB1 | WD repeat and SOCS box containing 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
| Symbol | Name |
|---|---|
| ACTB | actin, beta |
| ADRB2 | adrenoceptor beta 2, surface |
| AK4 | adenylate kinase 4 |
| ALCAM | activated leukocyte cell adhesion molecule |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| APOD | apolipoprotein D |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| CALD1 | caldesmon 1 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| CCNA2 | cyclin A2 |
| CCND1 | cyclin D1 |
| CCNF | cyclin F |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CDC25B | cell division cycle 25B |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CST1 | cystatin SN |
| CTSZ | cathepsin Z |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DENND2D | DENN/MADD domain containing 2D |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DMD | dystrophin |
| EBP | emopamil binding protein (sterol isomerase) |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| ELOVL6 | ELOVL fatty acid elongase 6 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B |
| ERLIN1 | ER lipid raft associated 1 |
| F12 | coagulation factor XII (Hageman factor) |
| FZD7 | frizzled class receptor 7 |
| GSTT1 | glutathione S-transferase theta 1 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit |
| HMGA2 | high mobility group AT-hook 2 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| IGFBP1 | insulin-like growth factor binding protein 1 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IRS1 | insulin receptor substrate 1 |
| IRS2 | insulin receptor substrate 2 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KDM5D | lysine (K)-specific demethylase 5D |
| KIF20A | kinesin family member 20A |
| KRT7 | keratin 7, type II |
| LDOC1 | leucine zipper, down-regulated in cancer 1 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LMNB1 | lamin B1 |
| MAP1B | microtubule-associated protein 1B |
| MGLL | monoglyceride lipase |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MYOF | myoferlin |
| NPTXR | neuronal pentraxin receptor |
| NPY1R | neuropeptide Y receptor Y1 |
| NREP | neuronal regeneration related protein |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OXTR | oxytocin receptor |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PIP | prolactin-induced protein |
| PLK1 | polo-like kinase 1 |
| POSTN | periostin, osteoblast specific factor |
| PRPF4 | pre-mRNA processing factor 4 |
| PRR7 | proline rich 7 (synaptic) |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SFRP1 | secreted frizzled-related protein 1 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SRPX | sushi-repeat containing protein, X-linked |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TBL1X | transducin (beta)-like 1X-linked |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TFF1 | trefoil factor 1 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMPRSS3 | transmembrane protease, serine 3 |
| TNC | tenascin C |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| TPM2 | tropomyosin 2 (beta) |
| TRIB2 | tribbles pseudokinase 2 |
| TUBA1A | tubulin, alpha 1a |
| TXNIP | thioredoxin interacting protein |
| USP9Y | ubiquitin specific peptidase 9, Y-linked |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZNF185 | zinc finger protein 185 (LIM domain) |
