| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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374 genes differentially expressed following the BRD-K88510285_B675700.cdx_VCAP_24.0_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABHD3 | abhydrolase domain containing 3 |
| ABHD4 | abhydrolase domain containing 4 |
| ADM | adrenomedullin |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ANKRD12 | ankyrin repeat domain 12 |
| ANXA2 | annexin A2 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| ASPN | asporin |
| ATF3 | activating transcription factor 3 |
| ATG4A | autophagy related 4A, cysteine peptidase |
| BACE2 | beta-site APP-cleaving enzyme 2 |
| BAG3 | BCL2-associated athanogene 3 |
| BMP2 | bone morphogenetic protein 2 |
| BTG2 | BTG family, member 2 |
| CA2 | carbonic anhydrase II |
| CADM1 | cell adhesion molecule 1 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD163 | CD163 molecule |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CD9 | CD9 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CHI3L2 | chitinase 3-like 2 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CLEC2B | C-type lectin domain family 2, member B |
| CLTB | clathrin, light chain B |
| COL11A1 | collagen, type XI, alpha 1 |
| COL15A1 | collagen, type XV, alpha 1 |
| COL1A1 | collagen, type I, alpha 1 |
| COL4A5 | collagen, type IV, alpha 5 |
| COL4A6 | collagen, type IV, alpha 6 |
| COL5A2 | collagen, type V, alpha 2 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) |
| CRYAB | crystallin, alpha B |
| CTGF | connective tissue growth factor |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| CTSE | cathepsin E |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYB5R2 | cytochrome b5 reductase 2 |
| CYTH1 | cytohesin 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
| DMD | dystrophin |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP14 | dual specificity phosphatase 14 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ELANE | elastase, neutrophil expressed |
| EMP1 | epithelial membrane protein 1 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 |
| FGF13 | fibroblast growth factor 13 |
| FN1 | fibronectin 1 |
| FOSL1 | FOS-like antigen 1 |
| FOSL2 | FOS-like antigen 2 |
| FOXO1 | forkhead box O1 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GCLC | glutamate-cysteine ligase, catalytic subunit |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GLA | galactosidase, alpha |
| GPC3 | glypican 3 |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HECA | headcase homolog (Drosophila) |
| HMOX1 | heme oxygenase 1 |
| HOXB2 | homeobox B2 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA2 | heat shock 70kDa protein 2 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPB8 | heat shock 22kDa protein 8 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFRD1 | interferon-related developmental regulator 1 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL6 | interleukin 6 |
| INHBA | inhibin, beta A |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JMJD6 | jumonji domain containing 6 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KLF6 | Kruppel-like factor 6 |
| KLF9 | Kruppel-like factor 9 |
| KLHL21 | kelch-like family member 21 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| KRT6A | keratin 6A, type II |
| KRT6B | keratin 6B, type II |
| KRT7 | keratin 7, type II |
| LIPG | lipase, endothelial |
| LOXL2 | lysyl oxidase-like 2 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MAN2B1 | mannosidase, alpha, class 2B, member 1 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta |
| MARCH3 | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MFAP5 | microfibrillar associated protein 5 |
| MIR22HG | MIR22 host gene |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MMP1 | matrix metallopeptidase 1 |
| MMP10 | matrix metallopeptidase 10 |
| MMP12 | matrix metallopeptidase 12 |
| MMP13 | matrix metallopeptidase 13 |
| MMP3 | matrix metallopeptidase 3 |
| MMP9 | matrix metallopeptidase 9 |
| MTCH1 | mitochondrial carrier 1 |
| NAMPT | nicotinamide phosphoribosyltransferase |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NRCAM | neuronal cell adhesion molecule |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| ODC1 | ornithine decarboxylase 1 |
| OFD1 | oral-facial-digital syndrome 1 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PEA15 | phosphoprotein enriched in astrocytes 15 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 |
| PIR | pirin (iron-binding nuclear protein) |
| PLAUR | plasminogen activator, urokinase receptor |
| PLBD1 | phospholipase B domain containing 1 |
| PLIN2 | perilipin 2 |
| POSTN | periostin, osteoblast specific factor |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTHLH | parathyroid hormone-like hormone |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGCC | regulator of cell cycle |
| RGS2 | regulator of G-protein signaling 2 |
| RIOK3 | RIO kinase 3 |
| S100P | S100 calcium binding protein P |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCG5 | secretogranin V |
| SCRG1 | stimulator of chondrogenesis 1 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SFRP4 | secreted frizzled-related protein 4 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| SST | somatostatin |
| TAC1 | tachykinin, precursor 1 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TMEM2 | transmembrane protein 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TOX3 | TOX high mobility group box family member 3 |
| TP53BP2 | tumor protein p53 binding protein 2 |
| TPM4 | tropomyosin 4 |
| TPP1 | tripeptidyl peptidase I |
| TRPS1 | trichorhinophalangeal syndrome I |
| TUBB2A | tubulin, beta 2A class IIa |
| TUBB2B | tubulin, beta 2B class IIb |
| TUBB6 | tubulin, beta 6 class V |
| TUFT1 | tuftelin 1 |
| TXNRD1 | thioredoxin reductase 1 |
| UBE2H | ubiquitin-conjugating enzyme E2H |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| WSB1 | WD repeat and SOCS box containing 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZFAND5 | zinc finger, AN1-type domain 5 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF165 | zinc finger protein 165 |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ACPP | acid phosphatase, prostate |
| AIM1 | absent in melanoma 1 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| ATP5G1 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) |
| ATP5I | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 |
| ATPIF1 | ATPase inhibitory factor 1 |
| AURKA | aurora kinase A |
| B3GNT1 | |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BIRC5 | baculoviral IAP repeat containing 5 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C7 | complement component 7 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 |
| CCDC85B | coiled-coil domain containing 85B |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CCNA2 | cyclin A2 |
| CCNB2 | cyclin B2 |
| CCND1 | cyclin D1 |
| CCNF | cyclin F |
| CDC20 | cell division cycle 20 |
| CDC25A | cell division cycle 25A |
| CDC25B | cell division cycle 25B |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CDK1 | cyclin-dependent kinase 1 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CENPA | centromere protein A |
| CENPE | centromere protein E, 312kDa |
| CENPU | centromere protein U |
| CHEK2 | checkpoint kinase 2 |
| CKLF | chemokine-like factor |
| CPA3 | carboxypeptidase A3 (mast cell) |
| CRISP3 | cysteine-rich secretory protein 3 |
| CSRP1 | cysteine and glycine-rich protein 1 |
| CYBA | cytochrome b-245, alpha polypeptide |
| DACH1 | dachshund family transcription factor 1 |
| DCK | deoxycytidine kinase |
| DCXR | dicarbonyl/L-xylulose reductase |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DHCR24 | 24-dehydrocholesterol reductase |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 |
| DPYSL2 | dihydropyrimidinase-like 2 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| DUT | deoxyuridine triphosphatase |
| EBP | emopamil binding protein (sterol isomerase) |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| EIF4B | eukaryotic translation initiation factor 4B |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| ELOVL6 | ELOVL fatty acid elongase 6 |
| EMP2 | epithelial membrane protein 2 |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) |
| ESR1 | estrogen receptor 1 |
| EVL | Enah/Vasp-like |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FAM111A | family with sequence similarity 111, member A |
| FEN1 | flap structure-specific endonuclease 1 |
| FOLR1 | folate receptor 1 (adult) |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| GATA2 | GATA binding protein 2 |
| GLOD4 | glyoxalase domain containing 4 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like |
| GSE1 | Gse1 coiled-coil protein |
| H2AFZ | H2A histone family, member Z |
| H2BFS | H2B histone family, member S (pseudogene) |
| HELLS | helicase, lymphoid-specific |
| HIST1H2BK | histone cluster 1, H2bk |
| HIST3H2A | histone cluster 3, H2a |
| HLTF | helicase-like transcription factor |
| HMG20B | high mobility group 20B |
| HMGB3 | high mobility group box 3 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| HN1 | hematological and neurological expressed 1 |
| HNMT | histamine N-methyltransferase |
| HOXA10 | homeobox A10 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| ICMT | isoprenylcysteine carboxyl methyltransferase |
| IFI44L | interferon-induced protein 44-like |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IFITM2 | interferon induced transmembrane protein 2 |
| IGF1R | insulin-like growth factor 1 receptor |
| KAZN | kazrin, periplakin interacting protein |
| KDM5D | lysine (K)-specific demethylase 5D |
| KIAA0101 | KIAA0101 |
| KIF11 | kinesin family member 11 |
| KIF15 | kinesin family member 15 |
| KIF18B | kinesin family member 18B |
| KIF20A | kinesin family member 20A |
| KIF23 | kinesin family member 23 |
| KIF2C | kinesin family member 2C |
| KLK2 | kallikrein-related peptidase 2 |
| KLK3 | kallikrein-related peptidase 3 |
| LAGE3 | L antigen family, member 3 |
| LBR | lamin B receptor |
| LEPR | leptin receptor |
| LIG1 | ligase I, DNA, ATP-dependent |
| LMNB1 | lamin B1 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MACROD1 | MACRO domain containing 1 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MCAM | melanoma cell adhesion molecule |
| MCM2 | minichromosome maintenance complex component 2 |
| MELK | maternal embryonic leucine zipper kinase |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| METRN | meteorin, glial cell differentiation regulator |
| MLPH | melanophilin |
| MRPL12 | mitochondrial ribosomal protein L12 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NCAPG | non-SMC condensin I complex, subunit G |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa |
| NDUFB1 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NEK2 | NIMA-related kinase 2 |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 |
| NREP | neuronal regeneration related protein |
| NUP210 | nucleoporin 210kDa |
| OXCT1 | 3-oxoacid CoA transferase 1 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PCNA | proliferating cell nuclear antigen |
| PDGFC | platelet derived growth factor C |
| PHGDH | phosphoglycerate dehydrogenase |
| PLCB4 | phospholipase C, beta 4 |
| PLK1 | polo-like kinase 1 |
| PLK4 | polo-like kinase 4 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa |
| PPA2 | pyrophosphatase (inorganic) 2 |
| PPIH | peptidylprolyl isomerase H (cyclophilin H) |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme |
| PRC1 | protein regulator of cytokinesis 1 |
| PRKCB | protein kinase C, beta |
| PRR7 | proline rich 7 (synaptic) |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTTG1 | pituitary tumor-transforming 1 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RAB26 | RAB26, member RAS oncogene family |
| RACGAP1 | Rac GTPase activating protein 1 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RAP1GAP | RAP1 GTPase activating protein |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RGS10 | regulator of G-protein signaling 10 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRM2 | ribonucleotide reductase M2 |
| SATB2 | SATB homeobox 2 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 |
| SORD | sorbitol dehydrogenase |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
| ST7 | suppression of tumorigenicity 7 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| STK39 | serine threonine kinase 39 |
| STMN1 | stathmin 1 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase |
| TARP | TCR gamma alternate reading frame protein |
| TBC1D16 | TBC1 domain family, member 16 |
| TFF3 | trefoil factor 3 (intestinal) |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TMEM5 | transmembrane protein 5 |
| TMPO | thymopoietin |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TPX2 | TPX2, microtubule-associated |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TRMT5 | tRNA methyltransferase 5 |
| TSPAN4 | tetraspanin 4 |
| TYMS | thymidylate synthetase |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZWINT | ZW10 interacting kinetochore protein |
