| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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107 genes differentially expressed following the BRD-K88573743_A443654_HME1_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABAT | 4-aminobutyrate aminotransferase |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| ALB | albumin |
| ALOX5 | arachidonate 5-lipoxygenase |
| ANKRD10 | ankyrin repeat domain 10 |
| ARG2 | arginase 2 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| C3 | complement component 3 |
| CD52 | CD52 molecule |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CFD | complement factor D (adipsin) |
| CHRDL1 | chordin-like 1 |
| CMC4 | C-x(9)-C motif containing 4 |
| CP | ceruloplasmin (ferroxidase) |
| CPE | carboxypeptidase E |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| ESR1 | estrogen receptor 1 |
| FCGBP | Fc fragment of IgG binding protein |
| GATA2 | GATA binding protein 2 |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPX2 | glutathione peroxidase 2 |
| HP | haptoglobin |
| IGHM | immunoglobulin heavy constant mu |
| IRS2 | insulin receptor substrate 2 |
| KRT15 | keratin 15, type I |
| LCK | LCK proto-oncogene, Src family tyrosine kinase |
| MT1F | metallothionein 1F |
| MXRA5 | matrix-remodelling associated 5 |
| OLFM4 | olfactomedin 4 |
| OXTR | oxytocin receptor |
| PDGFC | platelet derived growth factor C |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PRKCB | protein kinase C, beta |
| PTN | pleiotrophin |
| PTPRC | protein tyrosine phosphatase, receptor type, C |
| RBP1 | retinol binding protein 1, cellular |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
| SNX10 | sorting nexin 10 |
| SORD | sorbitol dehydrogenase |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| STC2 | stanniocalcin 2 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| SYBU | syntabulin (syntaxin-interacting) |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TFF3 | trefoil factor 3 (intestinal) |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TPP1 | tripeptidyl peptidase I |
| TSC22D3 | TSC22 domain family, member 3 |
| TSPAN6 | tetraspanin 6 |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| Symbol | Name |
|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| AGTR1 | angiotensin II receptor, type 1 |
| AK1 | adenylate kinase 1 |
| AXIN1 | axin 1 |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CPM | carboxypeptidase M |
| CTSZ | cathepsin Z |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| EFS | embryonal Fyn-associated substrate |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| HSPA2 | heat shock 70kDa protein 2 |
| ICAM1 | intercellular adhesion molecule 1 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| IL1B | interleukin 1, beta |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KDM3A | lysine (K)-specific demethylase 3A |
| KLF4 | Kruppel-like factor 4 (gut) |
| LAMC2 | laminin, gamma 2 |
| MAP7 | microtubule-associated protein 7 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MAT2A | methionine adenosyltransferase II, alpha |
| MGLL | monoglyceride lipase |
| NDRG1 | N-myc downstream regulated 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLS1 | plastin 1 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PPIF | peptidylprolyl isomerase F |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| S100A7 | S100 calcium binding protein A7 |
| SDC4 | syndecan 4 |
| SEC11A | SEC11 homolog A (S. cerevisiae) |
| SNAP25 | synaptosomal-associated protein, 25kDa |
| SNX11 | sorting nexin 11 |
| SRI | sorcin |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TBP | TATA box binding protein |
| THBS1 | thrombospondin 1 |
| TPBG | trophoblast glycoprotein |
| UGDH | UDP-glucose 6-dehydrogenase |
