| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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93 genes differentially expressed following the BRD-K88573743_A443654_HS578T_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ADIRF | adipogenesis regulatory factor |
| ASRGL1 | asparaginase like 1 |
| CD8A | CD8a molecule |
| CDC25B | cell division cycle 25B |
| CHRDL1 | chordin-like 1 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| DUSP6 | dual specificity phosphatase 6 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FGFR3 | fibroblast growth factor receptor 3 |
| GSTA1 | glutathione S-transferase alpha 1 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| H3F3B | H3 histone, family 3B (H3.3B) |
| HDAC6 | histone deacetylase 6 |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BK | histone cluster 1, H2bk |
| IDO1 | indoleamine 2,3-dioxygenase 1 |
| IGF1R | insulin-like growth factor 1 receptor |
| JUN | jun proto-oncogene |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 |
| KIAA0355 | KIAA0355 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| MYO5C | myosin VC |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLEK2 | pleckstrin 2 |
| PROM1 | prominin 1 |
| PRSS3 | protease, serine, 3 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
| STX1A | syntaxin 1A (brain) |
| TSTA3 | tissue specific transplantation antigen P35B |
| ZFPM2 | zinc finger protein, FOG family member 2 |
| Symbol | Name |
|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ATF5 | activating transcription factor 5 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| BMP7 | bone morphogenetic protein 7 |
| BST2 | bone marrow stromal cell antigen 2 |
| CADM1 | cell adhesion molecule 1 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DERA | deoxyribose-phosphate aldolase (putative) |
| DHCR24 | 24-dehydrocholesterol reductase |
| DHCR7 | 7-dehydrocholesterol reductase |
| FABP7 | fatty acid binding protein 7, brain |
| FDX1 | ferredoxin 1 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| GSTT1 | glutathione S-transferase theta 1 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 |
| HMOX1 | heme oxygenase 1 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| LMO4 | LIM domain only 4 |
| LOXL1 | lysyl oxidase-like 1 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| NEFH | neurofilament, heavy polypeptide |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| NREP | neuronal regeneration related protein |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PCCB | propionyl CoA carboxylase, beta polypeptide |
| PCP4 | Purkinje cell protein 4 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PGC | progastricsin (pepsinogen C) |
| PON2 | paraoxonase 2 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| QPRT | quinolinate phosphoribosyltransferase |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| SC5D | sterol-C5-desaturase |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SNAP25 | synaptosomal-associated protein, 25kDa |
| SOAT1 | sterol O-acyltransferase 1 |
| SPP1 | secreted phosphoprotein 1 |
| TBX2 | T-box 2 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| YAP1 | Yes-associated protein 1 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
