BRD-K88573743_A443654_SKBR3_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K88573743_A443654_SKBR3_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ALB albumin
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ANKRD10 ankyrin repeat domain 10
ANXA4 annexin A4
AQP9 aquaporin 9
BCL6 B-cell CLL/lymphoma 6
BHMT2 betaine--homocysteine S-methyltransferase 2
C5AR1 complement component 5a receptor 1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CRABP1 cellular retinoic acid binding protein 1
DYSF dysferlin
ECM2 extracellular matrix protein 2, female organ and adipocyte specific
FABP4 fatty acid binding protein 4, adipocyte
FN1 fibronectin 1
GAS1 growth arrest-specific 1
GCH1 GTP cyclohydrolase 1
GPNMB glycoprotein (transmembrane) nmb
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
ICMT isoprenylcysteine carboxyl methyltransferase
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IL17RB interleukin 17 receptor B
IRS2 insulin receptor substrate 2
KIAA0907 KIAA0907
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
METTL7A methyltransferase like 7A
MSRA methionine sulfoxide reductase A
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1H metallothionein 1H
MT2A metallothionein 2A
NAV2 neuron navigator 2
NR1H2 nuclear receptor subfamily 1, group H, member 2
PCBP2 poly(rC) binding protein 2
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PRDX2 peroxiredoxin 2
PTX3 pentraxin 3, long
RBP4 retinol binding protein 4, plasma
RGS5 regulator of G-protein signaling 5
RSRP1 arginine/serine-rich protein 1
SAMD4A sterile alpha motif domain containing 4A
SDC2 syndecan 2
SFRP1 secreted frizzled-related protein 1
TOB1 transducer of ERBB2, 1
UGCG UDP-glucose ceramide glucosyltransferase
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ADAM28 ADAM metallopeptidase domain 28
AMIGO2 adhesion molecule with Ig-like domain 2
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCNA2 cyclin A2
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CLCA4 chloride channel accessory 4
COG2 component of oligomeric golgi complex 2
DKK3 dickkopf WNT signaling pathway inhibitor 3
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
FAM129A family with sequence similarity 129, member A
FXYD5 FXYD domain containing ion transport regulator 5
JADE2 jade family PHD finger 2
JCHAIN joining chain of multimeric IgA and IgM
LCN2 lipocalin 2
MALL mal, T-cell differentiation protein-like
PFKP phosphofructokinase, platelet
PMM2 phosphomannomutase 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
RAE1 ribonucleic acid export 1
SRI sorcin
TBP TATA box binding protein
TUBB6 tubulin, beta 6 class V
Funding