Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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92 genes differentially expressed following the BRD-K88625236_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
ACTA1 | actin, alpha 1, skeletal muscle |
ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
ASNS | asparagine synthetase (glutamine-hydrolyzing) |
ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 |
CA2 | carbonic anhydrase II |
CD52 | CD52 molecule |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CRABP1 | cellular retinoic acid binding protein 1 |
CTGF | connective tissue growth factor |
DDIT4 | DNA-damage-inducible transcript 4 |
DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
DOCK4 | dedicator of cytokinesis 4 |
ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
FAM69A | family with sequence similarity 69, member A |
FRZB | frizzled-related protein |
GUSBP11 | glucuronidase, beta pseudogene 11 |
HMOX1 | heme oxygenase 1 |
HSPA13 | heat shock protein 70kDa family, member 13 |
IGHM | immunoglobulin heavy constant mu |
IGKV4-1 | immunoglobulin kappa variable 4-1 |
IGL | immunoglobulin lambda locus |
IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
IGLV2-23 | immunoglobulin lambda variable 2-23 |
MAP7 | microtubule-associated protein 7 |
MT1F | metallothionein 1F |
MTERF3 | mitochondrial transcription termination factor 3 |
NDRG1 | N-myc downstream regulated 1 |
NEB | nebulin |
NEFL | neurofilament, light polypeptide |
PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
PPAP2B | phosphatidic acid phosphatase type 2B |
PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
PRUNE2 | prune homolog 2 (Drosophila) |
RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
RFTN1 | raftlin, lipid raft linker 1 |
RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
SLC38A1 | solute carrier family 38, member 1 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SLN | sarcolipin |
STAB1 | stabilin 1 |
STC2 | stanniocalcin 2 |
TMEM176A | transmembrane protein 176A |
TMEM176B | transmembrane protein 176B |
TPD52L1 | tumor protein D52-like 1 |
TRAF5 | TNF receptor-associated factor 5 |
VEGFA | vascular endothelial growth factor A |
XBP1 | X-box binding protein 1 |
Symbol | Name |
---|---|
ADD3 | adducin 3 (gamma) |
ANXA1 | annexin A1 |
ANXA3 | annexin A3 |
ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
BEX1 | brain expressed, X-linked 1 |
CCNG1 | cyclin G1 |
CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
CLC | Charcot-Leyden crystal galectin |
CLEC11A | C-type lectin domain family 11, member A |
CPVL | carboxypeptidase, vitellogenic-like |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
CYR61 | cysteine-rich, angiogenic inducer, 61 |
DHCR24 | 24-dehydrocholesterol reductase |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
DLG5 | discs, large homolog 5 (Drosophila) |
FAM57A | family with sequence similarity 57, member A |
FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) |
GATA3 | GATA binding protein 3 |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
IGFBP4 | insulin-like growth factor binding protein 4 |
IL6ST | interleukin 6 signal transducer |
IRS2 | insulin receptor substrate 2 |
KRT4 | keratin 4, type II |
LCN2 | lipocalin 2 |
LDLR | low density lipoprotein receptor |
MNDA | myeloid cell nuclear differentiation antigen |
NQO1 | NAD(P)H dehydrogenase, quinone 1 |
PTGES | prostaglandin E synthase |
RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
S100A9 | S100 calcium binding protein A9 |
SAR1A | secretion associated, Ras related GTPase 1A |
SELL | selectin L |
SGPL1 | sphingosine-1-phosphate lyase 1 |
SORD | sorbitol dehydrogenase |
TBC1D4 | TBC1 domain family, member 4 |
TFPI2 | tissue factor pathway inhibitor 2 |
TGFA | transforming growth factor, alpha |
TKT | transketolase |
TM9SF3 | transmembrane 9 superfamily member 3 |
UBE2S | ubiquitin-conjugating enzyme E2S |
UGCG | UDP-glucose ceramide glucosyltransferase |
ZBTB18 | zinc finger and BTB domain containing 18 |