Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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140 genes differentially expressed following the BRD-K88742110_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABHD4 | abhydrolase domain containing 4 |
ALOX5 | arachidonate 5-lipoxygenase |
ANXA2 | annexin A2 |
AP1S2 | adaptor-related protein complex 1, sigma 2 subunit |
APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 |
ARG2 | arginase 2 |
CALML5 | calmodulin-like 5 |
CAPN2 | calpain 2, (m/II) large subunit |
CAST | calpastatin |
CCR1 | chemokine (C-C motif) receptor 1 |
CCR2 | chemokine (C-C motif) receptor 2 |
CD163 | CD163 molecule |
CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
CDK19 | cyclin-dependent kinase 19 |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CHN1 | chimerin 1 |
CLEC7A | C-type lectin domain family 7, member A |
CLGN | calmegin |
CSF1R | colony stimulating factor 1 receptor |
DEFB1 | defensin, beta 1 |
DEGS1 | delta(4)-desaturase, sphingolipid 1 |
DLK1 | delta-like 1 homolog (Drosophila) |
DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
DOK5 | docking protein 5 |
DPYD | dihydropyrimidine dehydrogenase |
DST | dystonin |
EDNRB | endothelin receptor type B |
EGFR | epidermal growth factor receptor |
FGF2 | fibroblast growth factor 2 (basic) |
FOXG1 | forkhead box G1 |
FTH1 | ferritin, heavy polypeptide 1 |
HMOX1 | heme oxygenase 1 |
HOXD1 | homeobox D1 |
HSPA1A | heat shock 70kDa protein 1A |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
IGFBP7 | insulin-like growth factor binding protein 7 |
IL10RA | interleukin 10 receptor, alpha |
INHBE | inhibin, beta E |
ITGB7 | integrin, beta 7 |
ITM2C | integral membrane protein 2C |
KIAA0907 | KIAA0907 |
LAPTM5 | lysosomal protein transmembrane 5 |
LOC100505650 | uncharacterized LOC100505650 |
LY86 | lymphocyte antigen 86 |
MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
MYBPC1 | myosin binding protein C, slow type |
N4BP2L1 | NEDD4 binding protein 2-like 1 |
NCF2 | neutrophil cytosolic factor 2 |
NEFL | neurofilament, light polypeptide |
NEFM | neurofilament, medium polypeptide |
PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
PIR | pirin (iron-binding nuclear protein) |
PRKCA | protein kinase C, alpha |
PRUNE2 | prune homolog 2 (Drosophila) |
RNASE6 | ribonuclease, RNase A family, k6 |
RTN2 | reticulon 2 |
S100A4 | S100 calcium binding protein A4 |
SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
SYT1 | synaptotagmin I |
TDO2 | tryptophan 2,3-dioxygenase |
TGFBI | transforming growth factor, beta-induced, 68kDa |
TPP1 | tripeptidyl peptidase I |
TRAF3IP3 | TRAF3 interacting protein 3 |
TTN | titin |
UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
ZBTB18 | zinc finger and BTB domain containing 18 |
Symbol | Name |
---|---|
ACACB | acetyl-CoA carboxylase beta |
AGR2 | anterior gradient 2 |
ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
AREG | amphiregulin |
ASPN | asporin |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
BAMBI | BMP and activin membrane-bound inhibitor |
CA12 | carbonic anhydrase XII |
CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
CHD7 | chromodomain helicase DNA binding protein 7 |
COL5A2 | collagen, type V, alpha 2 |
COMP | cartilage oligomeric matrix protein |
DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
DEPTOR | DEP domain containing MTOR-interacting protein |
EFNB2 | ephrin-B2 |
ELF1 | E74-like factor 1 (ets domain transcription factor) |
ELN | elastin |
ESR1 | estrogen receptor 1 |
F3 | coagulation factor III (thromboplastin, tissue factor) |
FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
FAM63A | family with sequence similarity 63, member A |
FNDC3B | fibronectin type III domain containing 3B |
FST | follistatin |
G0S2 | G0/G1 switch 2 |
GAS1 | growth arrest-specific 1 |
GPRC5A | G protein-coupled receptor, class C, group 5, member A |
GRWD1 | glutamate-rich WD repeat containing 1 |
GSTM3 | glutathione S-transferase mu 3 (brain) |
HES1 | hes family bHLH transcription factor 1 |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
ITGA6 | integrin, alpha 6 |
ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) |
KAT6B | K(lysine) acetyltransferase 6B |
KLF10 | Kruppel-like factor 10 |
LAMA3 | laminin, alpha 3 |
LAMB1 | laminin, beta 1 |
LTBP1 | latent transforming growth factor beta binding protein 1 |
MAN1C1 | mannosidase, alpha, class 1C, member 1 |
MFAP5 | microfibrillar associated protein 5 |
MGP | matrix Gla protein |
MXRA5 | matrix-remodelling associated 5 |
MYB | v-myb avian myeloblastosis viral oncogene homolog |
MYC | v-myc avian myelocytomatosis viral oncogene homolog |
MYO1B | myosin IB |
NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
NRN1 | neuritin 1 |
PLAGL1 | pleiomorphic adenoma gene-like 1 |
PLIN1 | perilipin 1 |
PRKCD | protein kinase C, delta |
RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
REG1A | regenerating islet-derived 1 alpha |
RRAGD | Ras-related GTP binding D |
RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
SFRP4 | secreted frizzled-related protein 4 |
SH3BP5 | SH3-domain binding protein 5 (BTK-associated) |
SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 |
SMAD3 | SMAD family member 3 |
SON | SON DNA binding protein |
SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
SRSF7 | serine/arginine-rich splicing factor 7 |
STC2 | stanniocalcin 2 |
SYBU | syntabulin (syntaxin-interacting) |
SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein |
TCF4 | transcription factor 4 |
THBS4 | thrombospondin 4 |
TIMP3 | TIMP metallopeptidase inhibitor 3 |
TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
TOB2 | transducer of ERBB2, 2 |
TSPAN13 | tetraspanin 13 |
TSPAN5 | tetraspanin 5 |
XBP1 | X-box binding protein 1 |