BRD-K88868628_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

25 genes differentially expressed following the BRD-K88868628_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADIRF adipogenesis regulatory factor
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ANPEP alanyl (membrane) aminopeptidase
CCL20 chemokine (C-C motif) ligand 20
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
GPNMB glycoprotein (transmembrane) nmb
HIST1H1C histone cluster 1, H1c
HMOX1 heme oxygenase 1
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
MAN1A1 mannosidase, alpha, class 1A, member 1
NQO1 NAD(P)H dehydrogenase, quinone 1
PLIN2 perilipin 2
RNASE4 ribonuclease, RNase A family, 4
SULF1 sulfatase 1
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
CDK4 cyclin-dependent kinase 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
HMGA2 high mobility group AT-hook 2
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
PLEKHA5 pleckstrin homology domain containing, family A member 5
RBP1 retinol binding protein 1, cellular
SLPI secretory leukocyte peptidase inhibitor
SRPX sushi-repeat containing protein, X-linked