BRD-K89329876_-666_HCC515_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-K89329876_-666_HCC515_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CD40 CD40 molecule, TNF receptor superfamily member 5
CSTA cystatin A (stefin A)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
KDM5D lysine (K)-specific demethylase 5D
MUC16 mucin 16, cell surface associated
PHLDA2 pleckstrin homology-like domain, family A, member 2
RPS4Y1 ribosomal protein S4, Y-linked 1
TFF1 trefoil factor 1
ZNF274 zinc finger protein 274

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
APOD apolipoprotein D
AQP1 aquaporin 1 (Colton blood group)
ATF3 activating transcription factor 3
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CAST calpastatin
CD36 CD36 molecule (thrombospondin receptor)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CXCL14 chemokine (C-X-C motif) ligand 14
GPI glucose-6-phosphate isomerase
LAMA4 laminin, alpha 4
LAMP1 lysosomal-associated membrane protein 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LPAR1 lysophosphatidic acid receptor 1
LPL lipoprotein lipase
MAP1B microtubule-associated protein 1B
MCOLN1 mucolipin 1
MT1M metallothionein 1M
PDGFD platelet derived growth factor D
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PRKACB protein kinase, cAMP-dependent, catalytic, beta
RBP1 retinol binding protein 1, cellular
RGL1 ral guanine nucleotide dissociation stimulator-like 1
SCG5 secretogranin V
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLPI secretory leukocyte peptidase inhibitor
SPARCL1 SPARC-like 1 (hevin)
STOM stomatin
TIMP3 TIMP metallopeptidase inhibitor 3
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
ZCCHC24 zinc finger, CCHC domain containing 24
Funding