| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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64 genes differentially expressed following the BRD-K89329876_-666_MCF7_24.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| CAPN2 | calpain 2, (m/II) large subunit |
| CAST | calpastatin |
| CDA | cytidine deaminase |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| FOSL1 | FOS-like antigen 1 |
| GLRX | glutaredoxin (thioltransferase) |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST2H2BE | histone cluster 2, H2be |
| HMG20B | high mobility group 20B |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| IER5 | immediate early response 5 |
| MALL | mal, T-cell differentiation protein-like |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MLPH | melanophilin |
| MTSS1 | metastasis suppressor 1 |
| PDLIM1 | PDZ and LIM domain 1 |
| PERP | PERP, TP53 apoptosis effector |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| S100A10 | S100 calcium binding protein A10 |
| SESN1 | sestrin 1 |
| ST5 | suppression of tumorigenicity 5 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| TPSAB1 | tryptase alpha/beta 1 |
| ZMAT3 | zinc finger, matrin-type 3 |
| Symbol | Name |
|---|---|
| ACAT1 | acetyl-CoA acetyltransferase 1 |
| ATAD2 | ATPase family, AAA domain containing 2 |
| AURKB | aurora kinase B |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CCNE2 | cyclin E2 |
| CDC45 | cell division cycle 45 |
| CDK1 | cyclin-dependent kinase 1 |
| CENPN | centromere protein N |
| CKS1B | CDC28 protein kinase regulatory subunit 1B |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EIF5A | eukaryotic translation initiation factor 5A |
| FANCI | Fanconi anemia, complementation group I |
| FKBP5 | FK506 binding protein 5 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| HAT1 | histone acetyltransferase 1 |
| IL1R1 | interleukin 1 receptor, type I |
| KIF11 | kinesin family member 11 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MELK | maternal embryonic leucine zipper kinase |
| MKI67 | marker of proliferation Ki-67 |
| MYH10 | myosin, heavy chain 10, non-muscle |
| NCAPH | non-SMC condensin I complex, subunit H |
| NDC80 | NDC80 kinetochore complex component |
| NPY | neuropeptide Y |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| OIP5 | Opa interacting protein 5 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| RRM2 | ribonucleotide reductase M2 |
| SMC2 | structural maintenance of chromosomes 2 |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| UBE2C | ubiquitin-conjugating enzyme E2C |
