BRD-K89329876_-666_VCAP_6.0_h_40.0_um Gene Set
Genes
63 genes differentially expressed following the BRD-K89329876_-666_VCAP_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
Symbol |
Name |
AKR1C3
|
aldo-keto reductase family 1, member C3
|
ANK3
|
ankyrin 3, node of Ranvier (ankyrin G)
|
C5ORF30
|
chromosome 5 open reading frame 30
|
CAST
|
calpastatin
|
CDH1
|
cadherin 1, type 1, E-cadherin (epithelial)
|
CDKN1A
|
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
|
COL3A1
|
collagen, type III, alpha 1
|
CST3
|
cystatin C
|
DSP
|
desmoplakin
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
FGF13
|
fibroblast growth factor 13
|
GATA2
|
GATA binding protein 2
|
GLRX
|
glutaredoxin (thioltransferase)
|
HPGD
|
hydroxyprostaglandin dehydrogenase 15-(NAD)
|
ID1
|
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
JUNB
|
jun B proto-oncogene
|
KLF4
|
Kruppel-like factor 4 (gut)
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
PERP
|
PERP, TP53 apoptosis effector
|
RGS2
|
regulator of G-protein signaling 2
|
RPS11
|
ribosomal protein S11
|
S100P
|
S100 calcium binding protein P
|
SGK1
|
serum/glucocorticoid regulated kinase 1
|
STEAP1
|
six transmembrane epithelial antigen of the prostate 1
|
STX1A
|
syntaxin 1A (brain)
|
TMSB15A
|
thymosin beta 15a
|
TRIB1
|
tribbles pseudokinase 1
|
decreased expression
Symbol |
Name |
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
C1ORF116
|
chromosome 1 open reading frame 116
|
C3
|
complement component 3
|
CD93
|
CD93 molecule
|
CDKN2A
|
cyclin-dependent kinase inhibitor 2A
|
COL10A1
|
collagen, type X, alpha 1
|
DKK3
|
dickkopf WNT signaling pathway inhibitor 3
|
DTL
|
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
|
ETV5
|
ets variant 5
|
FADS1
|
fatty acid desaturase 1
|
FGFBP1
|
fibroblast growth factor binding protein 1
|
HIST1H2BD
|
histone cluster 1, H2bd
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
HTRA1
|
HtrA serine peptidase 1
|
IFIT1
|
interferon-induced protein with tetratricopeptide repeats 1
|
LAMP3
|
lysosomal-associated membrane protein 3
|
LAPTM5
|
lysosomal protein transmembrane 5
|
MDK
|
midkine (neurite growth-promoting factor 2)
|
MT1E
|
metallothionein 1E
|
MT1X
|
metallothionein 1X
|
MX1
|
MX dynamin-like GTPase 1
|
NMU
|
neuromedin U
|
PDGFRL
|
platelet-derived growth factor receptor-like
|
PEG10
|
paternally expressed 10
|
PLN
|
phospholamban
|
PRKCDBP
|
protein kinase C, delta binding protein
|
PYCARD
|
PYD and CARD domain containing
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
SLC43A3
|
solute carrier family 43, member 3
|
SORL1
|
sortilin-related receptor, L(DLR class) A repeats containing
|
SOX4
|
SRY (sex determining region Y)-box 4
|
THBS1
|
thrombospondin 1
|
THBS2
|
thrombospondin 2
|
TMEM158
|
transmembrane protein 158 (gene/pseudogene)
|
TNS1
|
tensin 1
|