BRD-K89451433_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

71 genes differentially expressed following the BRD-K89451433_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRE5 adhesion G protein-coupled receptor E5
ALCAM activated leukocyte cell adhesion molecule
ANXA4 annexin A4
BTG1 B-cell translocation gene 1, anti-proliferative
C9ORF3 chromosome 9 open reading frame 3
CCDC92 coiled-coil domain containing 92
CCNA1 cyclin A1
CD36 CD36 molecule (thrombospondin receptor)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEMIP cell migration inducing protein, hyaluronan binding
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIC2 cysteine-rich hydrophobic domain 2
CIRBP cold inducible RNA binding protein
CLC Charcot-Leyden crystal galectin
COL8A2 collagen, type VIII, alpha 2
CSRP1 cysteine and glycine-rich protein 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
FABP4 fatty acid binding protein 4, adipocyte
FADS1 fatty acid desaturase 1
FAM13A family with sequence similarity 13, member A
FBP1 fructose-1,6-bisphosphatase 1
G0S2 G0/G1 switch 2
GLRX glutaredoxin (thioltransferase)
GPX2 glutathione peroxidase 2
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HYOU1 hypoxia up-regulated 1
IGFBP3 insulin-like growth factor binding protein 3
IL1B interleukin 1, beta
KCNK1 potassium channel, two pore domain subfamily K, member 1
KLF2 Kruppel-like factor 2
LGALS1 lectin, galactoside-binding, soluble, 1
MARCKSL1 MARCKS-like 1
MET MET proto-oncogene, receptor tyrosine kinase
NNMT nicotinamide N-methyltransferase
PLCB4 phospholipase C, beta 4
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RAB29 RAB29, member RAS oncogene family
RCAN1 regulator of calcineurin 1
RGS2 regulator of G-protein signaling 2
RHOB ras homolog family member B
RPS11 ribosomal protein S11
RPS4Y1 ribosomal protein S4, Y-linked 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SOX9 SRY (sex determining region Y)-box 9
SYNM synemin, intermediate filament protein
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TCTA T-cell leukemia translocation altered
THBS2 thrombospondin 2
TMEM2 transmembrane protein 2
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TP53I3 tumor protein p53 inducible protein 3
TPD52L1 tumor protein D52-like 1
XBP1 X-box binding protein 1

decreased expression

Symbol Name
CCND1 cyclin D1
CNPY3 canopy FGF signaling regulator 3
COL4A5 collagen, type IV, alpha 5
CXCL13 chemokine (C-X-C motif) ligand 13
EGFR epidermal growth factor receptor
HMGA2 high mobility group AT-hook 2
IGFBP7 insulin-like growth factor binding protein 7
MAGEA6 melanoma antigen family A6
MT1E metallothionein 1E
MT1X metallothionein 1X
PLTP phospholipid transfer protein
SFRP1 secreted frizzled-related protein 1
SLC26A3 solute carrier family 26 (anion exchanger), member 3
XIST X inactive specific transcript (non-protein coding)