BRD-K89930444_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-K89930444_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AK4 adenylate kinase 4
AKR1C3 aldo-keto reductase family 1, member C3
ASNS asparagine synthetase (glutamine-hydrolyzing)
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CAPN2 calpain 2, (m/II) large subunit
CAST calpastatin
CERK ceramide kinase
COL11A1 collagen, type XI, alpha 1
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CSTA cystatin A (stefin A)
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ENO2 enolase 2 (gamma, neuronal)
FGFR2 fibroblast growth factor receptor 2
FOLR1 folate receptor 1 (adult)
FTH1 ferritin, heavy polypeptide 1
FZD7 frizzled class receptor 7
GPX2 glutathione peroxidase 2
HEPH hephaestin
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
KRT5 keratin 5, type II
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAOB monoamine oxidase B
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NRN1 neuritin 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PDE4B phosphodiesterase 4B, cAMP-specific
PFKP phosphofructokinase, platelet
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
SCGB2A1 secretoglobin, family 2A, member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SETBP1 SET binding protein 1
SFN stratifin
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STC2 stanniocalcin 2
SYT1 synaptotagmin I
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
UGP2 UDP-glucose pyrophosphorylase 2
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
CCND2 cyclin D2
CPD carboxypeptidase D
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL14 chemokine (C-X-C motif) ligand 14
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GNAS GNAS complex locus
IL13RA2 interleukin 13 receptor, alpha 2
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MSL1 male-specific lethal 1 homolog (Drosophila)
MXRA5 matrix-remodelling associated 5
NPY neuropeptide Y
NRIP1 nuclear receptor interacting protein 1
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SORD sorbitol dehydrogenase
STAT1 signal transducer and activator of transcription 1, 91kDa
STX1A syntaxin 1A (brain)
TBX3 T-box 3
XIST X inactive specific transcript (non-protein coding)
Funding