BRD-K90382497_GW-843682X_LNCAP_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

104 genes differentially expressed following the BRD-K90382497_GW-843682X_LNCAP_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADRB2 adrenoceptor beta 2, surface
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
CCL20 chemokine (C-C motif) ligand 20
CDC20 cell division cycle 20
CDKN2A cyclin-dependent kinase inhibitor 2A
COL2A1 collagen, type II, alpha 1
CRYAB crystallin, alpha B
CST3 cystatin C
CXCL2 chemokine (C-X-C motif) ligand 2
EPCAM epithelial cell adhesion molecule
FAM46A family with sequence similarity 46, member A
FAS Fas cell surface death receptor
FGFR3 fibroblast growth factor receptor 3
FOLR1 folate receptor 1 (adult)
GSTT1 glutathione S-transferase theta 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HMGN3 high mobility group nucleosomal binding domain 3
HSPB8 heat shock 22kDa protein 8
METTL7A methyltransferase like 7A
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
PRF1 perforin 1 (pore forming protein)
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
RPL37A ribosomal protein L37a
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SFTPC surfactant protein C
SFTPD surfactant protein D
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SMYD2 SET and MYND domain containing 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
STEAP3 STEAP family member 3, metalloreductase
TGFBI transforming growth factor, beta-induced, 68kDa
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3

decreased expression

Symbol Name
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
APOD apolipoprotein D
APP amyloid beta (A4) precursor protein
ARHGAP29 Rho GTPase activating protein 29
ATXN1 ataxin 1
BASP1 brain abundant, membrane attached signal protein 1
CALD1 caldesmon 1
CALML3 calmodulin-like 3
CALML5 calmodulin-like 5
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2
CAST calpastatin
CAV1 caveolin 1, caveolae protein, 22kDa
CD44 CD44 molecule (Indian blood group)
CEMIP cell migration inducing protein, hyaluronan binding
CHGB chromogranin B
CLEC2B C-type lectin domain family 2, member B
COG5 component of oligomeric golgi complex 5
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTSK cathepsin K
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DLD dihydrolipoamide dehydrogenase
DPYSL2 dihydropyrimidinase-like 2
DSC3 desmocollin 3
EMP1 epithelial membrane protein 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FCGBP Fc fragment of IgG binding protein
FXYD5 FXYD domain containing ion transport regulator 5
GJA1 gap junction protein, alpha 1, 43kDa
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IGF1 insulin-like growth factor 1 (somatomedin C)
INHBB inhibin, beta B
LAMB1 laminin, beta 1
LYPLA1 lysophospholipase I
MARCKS myristoylated alanine-rich protein kinase C substrate
MTUS1 microtubule associated tumor suppressor 1
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NAMPT nicotinamide phosphoribosyltransferase
NPY neuropeptide Y
NRIP1 nuclear receptor interacting protein 1
NRP1 neuropilin 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PALLD palladin, cytoskeletal associated protein
PCP4 Purkinje cell protein 4
PDE4B phosphodiesterase 4B, cAMP-specific
PNMA2 paraneoplastic Ma antigen 2
PODXL podocalyxin-like
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
RGCC regulator of cell cycle
S100A7 S100 calcium binding protein A7
SDC1 syndecan 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SF1 splicing factor 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SNAP25 synaptosomal-associated protein, 25kDa
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SRGN serglycin
SYPL1 synaptophysin-like 1
TFPI2 tissue factor pathway inhibitor 2
THEMIS2 thymocyte selection associated family member 2
TPR translocated promoter region, nuclear basket protein
TSPYL5 TSPY-like 5
TST thiosulfate sulfurtransferase (rhodanese)
ZIC1 Zic family member 1
Funding