BRD-K90382497_GW-843682X_SKBR3_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-K90382497_GW-843682X_SKBR3_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALCAM activated leukocyte cell adhesion molecule
AUTS2 autism susceptibility candidate 2
BHLHE40 basic helix-loop-helix family, member e40
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CD24 CD24 molecule
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CELF2 CUGBP, Elav-like family member 2
COL14A1 collagen, type XIV, alpha 1
CSNK1E casein kinase 1, epsilon
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EDN1 endothelin 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EMP1 epithelial membrane protein 1
EREG epiregulin
FHL2 four and a half LIM domains 2
GADD45A growth arrest and DNA-damage-inducible, alpha
HNMT histamine N-methyltransferase
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IER5 immediate early response 5
KDM5D lysine (K)-specific demethylase 5D
KIAA0226L KIAA0226-like
KLF6 Kruppel-like factor 6
LIF leukemia inhibitory factor
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MT1E metallothionein 1E
NEBL nebulette
NRIP1 nuclear receptor interacting protein 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RND3 Rho family GTPase 3
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A2 S100 calcium binding protein A2
SDC4 syndecan 4
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SFN stratifin
TES testin LIM domain protein
TFF3 trefoil factor 3 (intestinal)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM45A transmembrane protein 45A
TNC tenascin C
UGCG UDP-glucose ceramide glucosyltransferase
WSB1 WD repeat and SOCS box containing 1
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ADCK3 aarF domain containing kinase 3
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AQP9 aquaporin 9
CBR3 carbonyl reductase 3
CD93 CD93 molecule
CPD carboxypeptidase D
CSTA cystatin A (stefin A)
CXCL13 chemokine (C-X-C motif) ligand 13
ELN elastin
FGFR2 fibroblast growth factor receptor 2
FGG fibrinogen gamma chain
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GPATCH8 G patch domain containing 8
GSTA1 glutathione S-transferase alpha 1
H2BFS H2B histone family, member S (pseudogene)
HIST1H2BK histone cluster 1, H2bk
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
KIF20A kinesin family member 20A
LAMP3 lysosomal-associated membrane protein 3
LTF lactotransferrin
NEFH neurofilament, heavy polypeptide
NRGN neurogranin (protein kinase C substrate, RC3)
PECAM1 platelet/endothelial cell adhesion molecule 1
PGC progastricsin (pepsinogen C)
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PODXL podocalyxin-like
RAD21 RAD21 homolog (S. pombe)
RGS2 regulator of G-protein signaling 2
RTN1 reticulon 1
S100A12 S100 calcium binding protein A12
SATB1 SATB homeobox 1
SPARCL1 SPARC-like 1 (hevin)
TRIB2 tribbles pseudokinase 2
TUSC3 tumor suppressor candidate 3
VLDLR very low density lipoprotein receptor
WARS tryptophanyl-tRNA synthetase
Funding