BRD-K90826279_-666_HA1E_24.0_h_20.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

44 genes differentially expressed following the BRD-K90826279_-666_HA1E_24.0_h_20.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CADM1 cell adhesion molecule 1
CD36 CD36 molecule (thrombospondin receptor)
CD40 CD40 molecule, TNF receptor superfamily member 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
EIF5A eukaryotic translation initiation factor 5A
FABP4 fatty acid binding protein 4, adipocyte
FRY furry homolog (Drosophila)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
KCTD12 potassium channel tetramerization domain containing 12
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NID1 nidogen 1
RGS5 regulator of G-protein signaling 5
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SFRP1 secreted frizzled-related protein 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TMEM47 transmembrane protein 47
TRIB3 tribbles pseudokinase 3
WDTC1 WD and tetratricopeptide repeats 1
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BHLHE41 basic helix-loop-helix family, member e41
CCL2 chemokine (C-C motif) ligand 2
CD24 CD24 molecule
CD69 CD69 molecule
CDC42 cell division cycle 42
CFB complement factor B
CXCL8 chemokine (C-X-C motif) ligand 8
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
IGHM immunoglobulin heavy constant mu
KLK6 kallikrein-related peptidase 6
LCN2 lipocalin 2
MAMLD1 mastermind-like domain containing 1
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MGP matrix Gla protein
PTPRC protein tyrosine phosphatase, receptor type, C
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBP1 retinol binding protein 1, cellular
RPL26L1 ribosomal protein L26-like 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLPI secretory leukocyte peptidase inhibitor
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TFRC transferrin receptor
TM4SF1 transmembrane 4 L six family member 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
Funding