BRD-K91263825_-666_HT29_6.0_h_10.0_um Gene Set
Genes
39 genes differentially expressed following the BRD-K91263825_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
Symbol |
Name |
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
ATP2B1
|
ATPase, Ca++ transporting, plasma membrane 1
|
CYP51A1
|
cytochrome P450, family 51, subfamily A, polypeptide 1
|
DHCR7
|
7-dehydrocholesterol reductase
|
EBP
|
emopamil binding protein (sterol isomerase)
|
FADS1
|
fatty acid desaturase 1
|
FASN
|
fatty acid synthase
|
FDPS
|
farnesyl diphosphate synthase
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
HSPA1A
|
heat shock 70kDa protein 1A
|
IDI1
|
isopentenyl-diphosphate delta isomerase 1
|
INSIG1
|
insulin induced gene 1
|
KDM5D
|
lysine (K)-specific demethylase 5D
|
LDLR
|
low density lipoprotein receptor
|
LPIN1
|
lipin 1
|
LSS
|
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
|
MSMO1
|
methylsterol monooxygenase 1
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
POR
|
P450 (cytochrome) oxidoreductase
|
PPP3CA
|
protein phosphatase 3, catalytic subunit, alpha isozyme
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
SCD
|
stearoyl-CoA desaturase (delta-9-desaturase)
|
SQLE
|
squalene epoxidase
|
SQSTM1
|
sequestosome 1
|
VIM
|
vimentin
|
decreased expression
Symbol |
Name |
ASCL1
|
achaete-scute family bHLH transcription factor 1
|
COTL1
|
coactosin-like F-actin binding protein 1
|
CPE
|
carboxypeptidase E
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
EDNRA
|
endothelin receptor type A
|
IGHM
|
immunoglobulin heavy constant mu
|
PALLD
|
palladin, cytoskeletal associated protein
|
PLS3
|
plastin 3
|
RGS2
|
regulator of G-protein signaling 2
|
SNX7
|
sorting nexin 7
|
TMEM176A
|
transmembrane protein 176A
|
TMEM176B
|
transmembrane protein 176B
|
XIST
|
X inactive specific transcript (non-protein coding)
|