BRD-K91509126_-666_A375_6.0_h_10.0_um Gene Set
Genes
49 genes differentially expressed following the BRD-K91509126_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
|
ADM
|
adrenomedullin
|
|
DDAH1
|
dimethylarginine dimethylaminohydrolase 1
|
|
DKK1
|
dickkopf WNT signaling pathway inhibitor 1
|
|
FTH1
|
ferritin, heavy polypeptide 1
|
|
GNAS
|
GNAS complex locus
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
|
HLA-DQA1
|
major histocompatibility complex, class II, DQ alpha 1
|
|
HMOX1
|
heme oxygenase 1
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
|
IGKV4-1
|
immunoglobulin kappa variable 4-1
|
|
INSIG1
|
insulin induced gene 1
|
|
MAPT
|
microtubule-associated protein tau
|
|
ME1
|
malic enzyme 1, NADP(+)-dependent, cytosolic
|
|
NDRG1
|
N-myc downstream regulated 1
|
|
RAPGEF5
|
Rap guanine nucleotide exchange factor (GEF) 5
|
|
SEL1L3
|
sel-1 suppressor of lin-12-like 3 (C. elegans)
|
|
SERPINE2
|
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
|
|
SERPING1
|
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
|
|
SULF1
|
sulfatase 1
|
|
TFPI
|
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
|
VEGFA
|
vascular endothelial growth factor A
|
decreased expression
| Symbol |
Name |
|
ACTG2
|
actin, gamma 2, smooth muscle, enteric
|
|
ATM
|
ATM serine/threonine kinase
|
|
ATP2B4
|
ATPase, Ca++ transporting, plasma membrane 4
|
|
CCND2
|
cyclin D2
|
|
CD24
|
CD24 molecule
|
|
COL5A2
|
collagen, type V, alpha 2
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
|
ESR1
|
estrogen receptor 1
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
|
FGF13
|
fibroblast growth factor 13
|
|
FGFR2
|
fibroblast growth factor receptor 2
|
|
GSN
|
gelsolin
|
|
HMG20B
|
high mobility group 20B
|
|
HMGB3
|
high mobility group box 3
|
|
HOPX
|
HOP homeobox
|
|
IGFBP5
|
insulin-like growth factor binding protein 5
|
|
ISOC1
|
isochorismatase domain containing 1
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
|
QKI
|
QKI, KH domain containing, RNA binding
|
|
QPCT
|
glutaminyl-peptide cyclotransferase
|
|
SCUBE2
|
signal peptide, CUB domain, EGF-like 2
|
|
STOM
|
stomatin
|
|
TCN1
|
transcobalamin I (vitamin B12 binding protein, R binder family)
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
