BRD-K91509126_-666_MCF7_6.0_h_10.0_um Gene Set
Genes
29 genes differentially expressed following the BRD-K91509126_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
ABCB6
|
ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
|
|
AKR1C1
|
aldo-keto reductase family 1, member C1
|
|
ALDH3A1
|
aldehyde dehydrogenase 3 family, member A1
|
|
CD58
|
CD58 molecule
|
|
GCLM
|
glutamate-cysteine ligase, modifier subunit
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
|
HMOX1
|
heme oxygenase 1
|
|
HOPX
|
HOP homeobox
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
|
MAFB
|
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
|
|
MAT2A
|
methionine adenosyltransferase II, alpha
|
|
ME1
|
malic enzyme 1, NADP(+)-dependent, cytosolic
|
|
MSMO1
|
methylsterol monooxygenase 1
|
|
NQO1
|
NAD(P)H dehydrogenase, quinone 1
|
|
PGD
|
phosphogluconate dehydrogenase
|
|
PSMB3
|
proteasome (prosome, macropain) subunit, beta type, 3
|
|
SCD
|
stearoyl-CoA desaturase (delta-9-desaturase)
|
|
SLC7A11
|
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
|
|
TSKU
|
tsukushi, small leucine rich proteoglycan
|
|
TXNRD1
|
thioredoxin reductase 1
|
decreased expression
| Symbol |
Name |
|
CKB
|
creatine kinase, brain
|
|
EIF5B
|
eukaryotic translation initiation factor 5B
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
|
GOLGA8A
|
golgin A8 family, member A
|
|
GOLGA8B
|
golgin A8 family, member B
|
|
HECA
|
headcase homolog (Drosophila)
|
|
LTBP3
|
latent transforming growth factor beta binding protein 3
|
|
SERPINF1
|
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
|
|
ZEB1
|
zinc finger E-box binding homeobox 1
|
