Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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81 genes differentially expressed following the BRD-K92049597_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ACKR3 | atypical chemokine receptor 3 |
ACTA1 | actin, alpha 1, skeletal muscle |
CCDC86 | coiled-coil domain containing 86 |
CD9 | CD9 molecule |
CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
CLC | Charcot-Leyden crystal galectin |
DCN | decorin |
DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
FAM69A | family with sequence similarity 69, member A |
GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
HILPDA | hypoxia inducible lipid droplet-associated |
HYOU1 | hypoxia up-regulated 1 |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
IGFBP5 | insulin-like growth factor binding protein 5 |
KLHL41 | kelch-like family member 41 |
KRT6A | keratin 6A, type II |
LDB3 | LIM domain binding 3 |
LOC100505650 | uncharacterized LOC100505650 |
MAP7 | microtubule-associated protein 7 |
MB | myoglobin |
MTERF3 | mitochondrial transcription termination factor 3 |
NEB | nebulin |
NNMT | nicotinamide N-methyltransferase |
PDE4DIP | phosphodiesterase 4D interacting protein |
PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
PRUNE2 | prune homolog 2 (Drosophila) |
RGCC | regulator of cell cycle |
RGS5 | regulator of G-protein signaling 5 |
RPS5 | ribosomal protein S5 |
RRAS2 | related RAS viral (r-ras) oncogene homolog 2 |
RRP8 | ribosomal RNA processing 8, methyltransferase, homolog (yeast) |
SCGB2A1 | secretoglobin, family 2A, member 1 |
SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
SLN | sarcolipin |
TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
TNNI2 | troponin I type 2 (skeletal, fast) |
TPM1 | tropomyosin 1 (alpha) |
TTN | titin |
TWIST1 | twist family bHLH transcription factor 1 |
VCAM1 | vascular cell adhesion molecule 1 |
Symbol | Name |
---|---|
ACTN1 | actinin, alpha 1 |
AREG | amphiregulin |
ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 |
C1ORF106 | chromosome 1 open reading frame 106 |
CCL19 | chemokine (C-C motif) ligand 19 |
CCNF | cyclin F |
CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
CHMP4A | charged multivesicular body protein 4A |
COL4A2 | collagen, type IV, alpha 2 |
COL6A3 | collagen, type VI, alpha 3 |
CTSH | cathepsin H |
CYR61 | cysteine-rich, angiogenic inducer, 61 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
FAM46A | family with sequence similarity 46, member A |
FOLR1 | folate receptor 1 (adult) |
IFI27 | interferon, alpha-inducible protein 27 |
IGFBP7 | insulin-like growth factor binding protein 7 |
IL7R | interleukin 7 receptor |
IRS2 | insulin receptor substrate 2 |
ITGA6 | integrin, alpha 6 |
KIF14 | kinesin family member 14 |
LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
MGP | matrix Gla protein |
NT5E | 5'-nucleotidase, ecto (CD73) |
PLA2G16 | phospholipase A2, group XVI |
PLAC8 | placenta-specific 8 |
PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
PNMA1 | paraneoplastic Ma antigen 1 |
PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform |
SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
SLC22A3 | solute carrier family 22 (organic cation transporter), member 3 |
SOX9 | SRY (sex determining region Y)-box 9 |
SPOP | speckle-type POZ protein |
SPTBN1 | spectrin, beta, non-erythrocytic 1 |
SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
TFPI2 | tissue factor pathway inhibitor 2 |
TGFBI | transforming growth factor, beta-induced, 68kDa |
TMC5 | transmembrane channel-like 5 |
TOP2A | topoisomerase (DNA) II alpha 170kDa |