BRD-K92093830_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

199 genes differentially expressed following the BRD-K92093830_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
AEBP1 AE binding protein 1
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALOX5 arachidonate 5-lipoxygenase
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ASPN asporin
ASS1 argininosuccinate synthase 1
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
BTG2 BTG family, member 2
C1QA complement component 1, q subcomponent, A chain
CA12 carbonic anhydrase XII
CADM1 cell adhesion molecule 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCL4 chemokine (C-C motif) ligand 4
CD24 CD24 molecule
CES2 carboxylesterase 2
CHODL chondrolectin
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CKB creatine kinase, brain
CKM creatine kinase, muscle
CLDN3 claudin 3
COL3A1 collagen, type III, alpha 1
COLEC12 collectin sub-family member 12
CPE carboxypeptidase E
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
DCN decorin
EDNRA endothelin receptor type A
EGFL6 EGF-like-domain, multiple 6
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EXPH5 exophilin 5
FBLN1 fibulin 1
FBN2 fibrillin 2
FHL1 four and a half LIM domains 1
FOXF1 forkhead box F1
FRY furry homolog (Drosophila)
FXYD6 FXYD domain containing ion transport regulator 6
GADD45B growth arrest and DNA-damage-inducible, beta
GBP1 guanylate binding protein 1, interferon-inducible
GJA1 gap junction protein, alpha 1, 43kDa
GSE1 Gse1 coiled-coil protein
HBB hemoglobin, beta
HILPDA hypoxia inducible lipid droplet-associated
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
ICAM1 intercellular adhesion molecule 1
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP5 insulin-like growth factor binding protein 5
IL1R1 interleukin 1 receptor, type I
IL32 interleukin 32
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KLHL41 kelch-like family member 41
KRT8 keratin 8, type II
LAMP3 lysosomal-associated membrane protein 3
LMO3 LIM domain only 3 (rhombotin-like 2)
LRRC17 leucine rich repeat containing 17
LTBP1 latent transforming growth factor beta binding protein 1
MAOA monoamine oxidase A
MB myoglobin
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MMP12 matrix metallopeptidase 12
MPPED2 metallophosphoesterase domain containing 2
MTMR11 myotubularin related protein 11
MTSS1 metastasis suppressor 1
MXRA5 matrix-remodelling associated 5
NBL1 neuroblastoma 1, DAN family BMP antagonist
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NEB nebulin
NID2 nidogen 2 (osteonidogen)
NLRP2 NLR family, pyrin domain containing 2
NPR3 natriuretic peptide receptor 3
NUPR1 nuclear protein, transcriptional regulator, 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PBX3 pre-B-cell leukemia homeobox 3
PCP4 Purkinje cell protein 4
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PLVAP plasmalemma vesicle associated protein
PTN pleiotrophin
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RCAN2 regulator of calcineurin 2
RGCC regulator of cell cycle
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
S100A8 S100 calcium binding protein A8
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLC12A8 solute carrier family 12, member 8
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPON1 spondin 1, extracellular matrix protein
SULF1 sulfatase 1
TCF21 transcription factor 21
TGFB3 transforming growth factor, beta 3
TKTL1 transketolase-like 1
TMEM259 transmembrane protein 259
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TRIL TLR4 interactor with leucine-rich repeats
TTC39A tetratricopeptide repeat domain 39A
TTN titin
TXNIP thioredoxin interacting protein
XIST X inactive specific transcript (non-protein coding)
ZDHHC11 zinc finger, DHHC-type containing 11
ZFPM2 zinc finger protein, FOG family member 2

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
AQP3 aquaporin 3 (Gill blood group)
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
BICD2 bicaudal D homolog 2 (Drosophila)
CBFB core-binding factor, beta subunit
CCNA2 cyclin A2
CCNB2 cyclin B2
CCNF cyclin F
CDH19 cadherin 19, type 2
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHD1 chromodomain helicase DNA binding protein 1
CNOT7 CCR4-NOT transcription complex, subunit 7
CXCL12 chemokine (C-X-C motif) ligand 12
DDIT4 DNA-damage-inducible transcript 4
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
DUSP7 dual specificity phosphatase 7
EDNRB endothelin receptor type B
ERBB3 erb-b2 receptor tyrosine kinase 3
FGF13 fibroblast growth factor 13
FOSL1 FOS-like antigen 1
FSCN1 fascin actin-bundling protein 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
HAT1 histone acetyltransferase 1
HOXC6 homeobox C6
HSPA8 heat shock 70kDa protein 8
IER3 immediate early response 3
IGF1R insulin-like growth factor 1 receptor
IRS2 insulin receptor substrate 2
ITGA6 integrin, alpha 6
JMJD6 jumonji domain containing 6
KIF14 kinesin family member 14
KIF23 kinesin family member 23
KLF4 Kruppel-like factor 4 (gut)
KRT10 keratin 10, type I
KRT14 keratin 14, type I
KRT17 keratin 17, type I
LDLR low density lipoprotein receptor
MAT2A methionine adenosyltransferase II, alpha
MIA melanoma inhibitory activity
MKI67 marker of proliferation Ki-67
MOK MOK protein kinase
NET1 neuroepithelial cell transforming 1
NME4 NME/NM23 nucleoside diphosphate kinase 4
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRIP1 nuclear receptor interacting protein 1
NUP98 nucleoporin 98kDa
PARP2 poly (ADP-ribose) polymerase 2
PDCD2 programmed cell death 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLK1 polo-like kinase 1
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PRKCA protein kinase C, alpha
PROM1 prominin 1
PTP4A2 protein tyrosine phosphatase type IVA, member 2
PTPN12 protein tyrosine phosphatase, non-receptor type 12
QKI QKI, KH domain containing, RNA binding
RBMS1 RNA binding motif, single stranded interacting protein 1
RND3 Rho family GTPase 3
RPS11 ribosomal protein S11
S100B S100 calcium binding protein B
SFRP1 secreted frizzled-related protein 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMNDC1 survival motor neuron domain containing 1
SOX10 SRY (sex determining region Y)-box 10
SOX9 SRY (sex determining region Y)-box 9
SPC25 SPC25, NDC80 kinetochore complex component
SPRY2 sprouty homolog 2 (Drosophila)
SSFA2 sperm specific antigen 2
SUMO3 small ubiquitin-like modifier 3
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM47 transmembrane protein 47
TNC tenascin C
TSC22D2 TSC22 domain family, member 2
TUBA4A tubulin, alpha 4a
TXLNA taxilin alpha
UBE2C ubiquitin-conjugating enzyme E2C
WIPF2 WAS/WASL interacting protein family, member 2
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta