| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
85 genes differentially expressed following the BRD-K92107474_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 |
| ALOX5 | arachidonate 5-lipoxygenase |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| AUTS2 | autism susceptibility candidate 2 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| COL11A1 | collagen, type XI, alpha 1 |
| COL1A1 | collagen, type I, alpha 1 |
| DCN | decorin |
| EGR3 | early growth response 3 |
| FN1 | fibronectin 1 |
| FOXO1 | forkhead box O1 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) |
| HMOX1 | heme oxygenase 1 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| MMP9 | matrix metallopeptidase 9 |
| NID2 | nidogen 2 (osteonidogen) |
| NKX3-1 | NK3 homeobox 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| RBP4 | retinol binding protein 4, plasma |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| SCGB1D2 | secretoglobin, family 1D, member 2 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
| SORD | sorbitol dehydrogenase |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| THY1 | Thy-1 cell surface antigen |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TSPAN5 | tetraspanin 5 |
| ZNF331 | zinc finger protein 331 |
| Symbol | Name |
|---|---|
| ACTB | actin, beta |
| ADAMDEC1 | ADAM-like, decysin 1 |
| AHR | aryl hydrocarbon receptor |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| BEX1 | brain expressed, X-linked 1 |
| CD58 | CD58 molecule |
| CES2 | carboxylesterase 2 |
| CHEK1 | checkpoint kinase 1 |
| CLTB | clathrin, light chain B |
| CSTA | cystatin A (stefin A) |
| DSC2 | desmocollin 2 |
| EIF5 | eukaryotic translation initiation factor 5 |
| EPAS1 | endothelial PAS domain protein 1 |
| EXT1 | exostosin glycosyltransferase 1 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| HEPH | hephaestin |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HN1 | hematological and neurological expressed 1 |
| KIF14 | kinesin family member 14 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog |
| KRT6B | keratin 6B, type II |
| LYZ | lysozyme |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAPK6 | mitogen-activated protein kinase 6 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| NXT2 | nuclear transport factor 2-like export factor 2 |
| OLFM4 | olfactomedin 4 |
| PALLD | palladin, cytoskeletal associated protein |
| PLAC8 | placenta-specific 8 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) |
| PTEN | phosphatase and tensin homolog |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| PXMP2 | peroxisomal membrane protein 2, 22kDa |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| REG1A | regenerating islet-derived 1 alpha |
| REG3A | regenerating islet-derived 3 alpha |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| STK38L | serine/threonine kinase 38 like |
| SUB1 | SUB1 homolog (S. cerevisiae) |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) |
| TACC2 | transforming, acidic coiled-coil containing protein 2 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM5 | transmembrane protein 5 |
