BRD-K92301463_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

20 genes differentially expressed following the BRD-K92301463_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AUTS2 autism susceptibility candidate 2
C6ORF62 chromosome 6 open reading frame 62
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLIC4 chloride intracellular channel 4
DUSP1 dual specificity phosphatase 1
GCLM glutamate-cysteine ligase, modifier subunit
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
KYNU kynureninase

decreased expression

Symbol Name
DDIT4 DNA-damage-inducible transcript 4
HES1 hes family bHLH transcription factor 1
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PPARG peroxisome proliferator-activated receptor gamma
PRAME preferentially expressed antigen in melanoma
TIPARP TCDD-inducible poly(ADP-ribose) polymerase