| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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149 genes differentially expressed following the BRD-K92428232_GSK-461364_A375_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABHD2 | abhydrolase domain containing 2 |
| ACTN1 | actinin, alpha 1 |
| AGTR1 | angiotensin II receptor, type 1 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) |
| ANPEP | alanyl (membrane) aminopeptidase |
| ASS1 | argininosuccinate synthase 1 |
| ATF3 | activating transcription factor 3 |
| AZU1 | azurocidin 1 |
| CCND2 | cyclin D2 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CFB | complement factor B |
| CLC | Charcot-Leyden crystal galectin |
| COCH | cochlin |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CTSW | cathepsin W |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| EGR1 | early growth response 1 |
| EGR2 | early growth response 2 |
| ELANE | elastase, neutrophil expressed |
| ELF1 | E74-like factor 1 (ets domain transcription factor) |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GLUL | glutamate-ammonia ligase |
| H2BFS | H2B histone family, member S (pseudogene) |
| HBEGF | heparin-binding EGF-like growth factor |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BE | histone cluster 1, H2be |
| HIST1H2BF | histone cluster 1, H2bf |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H2BH | histone cluster 1, H2bh |
| HIST1H2BK | histone cluster 1, H2bk |
| HNMT | histamine N-methyltransferase |
| HOMER1 | homer scaffolding protein 1 |
| HSPB8 | heat shock 22kDa protein 8 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IL1RN | interleukin 1 receptor antagonist |
| KCTD5 | potassium channel tetramerization domain containing 5 |
| KLHDC10 | kelch domain containing 10 |
| LCN2 | lipocalin 2 |
| LRRC59 | leucine rich repeat containing 59 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LTF | lactotransferrin |
| MEIS2 | Meis homeobox 2 |
| MMP7 | matrix metallopeptidase 7 |
| MMP9 | matrix metallopeptidase 9 |
| MSRA | methionine sulfoxide reductase A |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| NFE2L2 | nuclear factor, erythroid 2-like 2 |
| NOP16 | NOP16 nucleolar protein |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| OLFM4 | olfactomedin 4 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 |
| PRSS2 | protease, serine, 2 (trypsin 2) |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RBM25 | RNA binding motif protein 25 |
| REG1A | regenerating islet-derived 1 alpha |
| SDC2 | syndecan 2 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPON1 | spondin 1, extracellular matrix protein |
| STAT1 | signal transducer and activator of transcription 1, 91kDa |
| STK38L | serine/threonine kinase 38 like |
| TARP | TCR gamma alternate reading frame protein |
| TCL1A | T-cell leukemia/lymphoma 1A |
| TPM1 | tropomyosin 1 (alpha) |
| VDAC1 | voltage-dependent anion channel 1 |
| ZEB2 | zinc finger E-box binding homeobox 2 |
| ZMAT3 | zinc finger, matrin-type 3 |
| Symbol | Name |
|---|---|
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALDOC | aldolase C, fructose-bisphosphate |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| BTBD3 | BTB (POZ) domain containing 3 |
| CADM1 | cell adhesion molecule 1 |
| CALR | calreticulin |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| CAPN3 | calpain 3, (p94) |
| CCNE2 | cyclin E2 |
| CCNF | cyclin F |
| CD59 | CD59 molecule, complement regulatory protein |
| CDCA4 | cell division cycle associated 4 |
| CDK1 | cyclin-dependent kinase 1 |
| CKAP4 | cytoskeleton-associated protein 4 |
| CLEC7A | C-type lectin domain family 7, member A |
| COL6A1 | collagen, type VI, alpha 1 |
| EFNA1 | ephrin-A1 |
| ENO2 | enolase 2 (gamma, neuronal) |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FN1 | fibronectin 1 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| HELLS | helicase, lymphoid-specific |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha |
| HSPA1A | heat shock 70kDa protein 1A |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| MAP1B | microtubule-associated protein 1B |
| MBP | myelin basic protein |
| METRN | meteorin, glial cell differentiation regulator |
| NAV2 | neuron navigator 2 |
| NISCH | nischarin |
| NLRP2 | NLR family, pyrin domain containing 2 |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| NVL | nuclear VCP-like |
| OPHN1 | oligophrenin 1 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PLIN2 | perilipin 2 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide |
| PSPH | phosphoserine phosphatase |
| RPL27A | ribosomal protein L27a |
| RPL37A | ribosomal protein L37a |
| RPL38 | ribosomal protein L38 |
| RPS11 | ribosomal protein S11 |
| RRM2 | ribonucleotide reductase M2 |
| SCGB1D2 | secretoglobin, family 1D, member 2 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| STATH | statherin |
| SVIL | supervillin |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TUBB2A | tubulin, beta 2A class IIa |
| UBE2A | ubiquitin-conjugating enzyme E2A |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UGP2 | UDP-glucose pyrophosphorylase 2 |
| WEE1 | WEE1 G2 checkpoint kinase |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZNF589 | zinc finger protein 589 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
