BRD-K92428232_GSK-461364_A549_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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42 genes differentially expressed following the BRD-K92428232_GSK-461364_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AURKA aurora kinase A
CAPG capping protein (actin filament), gelsolin-like
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
COL4A2 collagen, type IV, alpha 2
CRYAB crystallin, alpha B
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
GSN gelsolin
KRT15 keratin 15, type I
LIMCH1 LIM and calponin homology domains 1
NFIL3 nuclear factor, interleukin 3 regulated
NPC1 Niemann-Pick disease, type C1
PTGDS prostaglandin D2 synthase 21kDa (brain)
S100A2 S100 calcium binding protein A2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
STK26 serine/threonine protein kinase 26
TACSTD2 tumor-associated calcium signal transducer 2
TRIB2 tribbles pseudokinase 2

decreased expression

Symbol Name
CD200 CD200 molecule
CD99 CD99 molecule
CDCA4 cell division cycle associated 4
CDK1 cyclin-dependent kinase 1
CIRBP cold inducible RNA binding protein
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GRK5 G protein-coupled receptor kinase 5
HES1 hes family bHLH transcription factor 1
HOXC6 homeobox C6
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
ISOC1 isochorismatase domain containing 1
LRRC17 leucine rich repeat containing 17
NID2 nidogen 2 (osteonidogen)
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PLSCR4 phospholipid scramblase 4
PXMP2 peroxisomal membrane protein 2, 22kDa
SCG2 secretogranin II
SRSF6 serine/arginine-rich splicing factor 6
THBS2 thrombospondin 2
UBE2C ubiquitin-conjugating enzyme E2C
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
WWTR1 WW domain containing transcription regulator 1
ZFPM2 zinc finger protein, FOG family member 2