BRD-K92428232_GSK-461364_A549_24_h_3.33_um Gene Set
Genes
42 genes differentially expressed following the BRD-K92428232_GSK-461364_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
|
AURKA
|
aurora kinase A
|
|
CAPG
|
capping protein (actin filament), gelsolin-like
|
|
CBLB
|
Cbl proto-oncogene B, E3 ubiquitin protein ligase
|
|
COL4A2
|
collagen, type IV, alpha 2
|
|
CRYAB
|
crystallin, alpha B
|
|
FCER1A
|
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
|
|
GSN
|
gelsolin
|
|
KRT15
|
keratin 15, type I
|
|
LIMCH1
|
LIM and calponin homology domains 1
|
|
NFIL3
|
nuclear factor, interleukin 3 regulated
|
|
NPC1
|
Niemann-Pick disease, type C1
|
|
PTGDS
|
prostaglandin D2 synthase 21kDa (brain)
|
|
S100A2
|
S100 calcium binding protein A2
|
|
SCD
|
stearoyl-CoA desaturase (delta-9-desaturase)
|
|
STK26
|
serine/threonine protein kinase 26
|
|
TACSTD2
|
tumor-associated calcium signal transducer 2
|
|
TRIB2
|
tribbles pseudokinase 2
|
decreased expression
| Symbol |
Name |
|
CD200
|
CD200 molecule
|
|
CD99
|
CD99 molecule
|
|
CDCA4
|
cell division cycle associated 4
|
|
CDK1
|
cyclin-dependent kinase 1
|
|
CIRBP
|
cold inducible RNA binding protein
|
|
CPS1
|
carbamoyl-phosphate synthase 1, mitochondrial
|
|
GNG11
|
guanine nucleotide binding protein (G protein), gamma 11
|
|
GRK5
|
G protein-coupled receptor kinase 5
|
|
HES1
|
hes family bHLH transcription factor 1
|
|
HOXC6
|
homeobox C6
|
|
HSD17B2
|
hydroxysteroid (17-beta) dehydrogenase 2
|
|
ISOC1
|
isochorismatase domain containing 1
|
|
LRRC17
|
leucine rich repeat containing 17
|
|
NID2
|
nidogen 2 (osteonidogen)
|
|
PAPSS2
|
3'-phosphoadenosine 5'-phosphosulfate synthase 2
|
|
PLSCR4
|
phospholipid scramblase 4
|
|
PXMP2
|
peroxisomal membrane protein 2, 22kDa
|
|
SCG2
|
secretogranin II
|
|
SRSF6
|
serine/arginine-rich splicing factor 6
|
|
THBS2
|
thrombospondin 2
|
|
UBE2C
|
ubiquitin-conjugating enzyme E2C
|
|
UGT2B28
|
UDP glucuronosyltransferase 2 family, polypeptide B28
|
|
WWTR1
|
WW domain containing transcription regulator 1
|
|
ZFPM2
|
zinc finger protein, FOG family member 2
|
