Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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121 genes differentially expressed following the BRD-K92428232_GSK-461364_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
ABHD6 | abhydrolase domain containing 6 |
AURKA | aurora kinase A |
AUTS2 | autism susceptibility candidate 2 |
CEMIP | cell migration inducing protein, hyaluronan binding |
CHD7 | chromodomain helicase DNA binding protein 7 |
CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
CLDN3 | claudin 3 |
CLEC2B | C-type lectin domain family 2, member B |
COCH | cochlin |
CTSZ | cathepsin Z |
DLK1 | delta-like 1 homolog (Drosophila) |
EPHB2 | EPH receptor B2 |
FABP4 | fatty acid binding protein 4, adipocyte |
FBN2 | fibrillin 2 |
FSCN1 | fascin actin-bundling protein 1 |
GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 |
GPRC5B | G protein-coupled receptor, class C, group 5, member B |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
ITGA6 | integrin, alpha 6 |
KCTD5 | potassium channel tetramerization domain containing 5 |
KRT23 | keratin 23, type I |
KTN1 | kinectin 1 (kinesin receptor) |
LAMB3 | laminin, beta 3 |
LAMC2 | laminin, gamma 2 |
LIMS1 | LIM and senescent cell antigen-like domains 1 |
LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
LYPD1 | LY6/PLAUR domain containing 1 |
MECOM | MDS1 and EVI1 complex locus |
MMD | monocyte to macrophage differentiation-associated |
MTA1 | metastasis associated 1 |
MUC16 | mucin 16, cell surface associated |
PIP | prolactin-induced protein |
PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
PRRC2C | proline-rich coiled-coil 2C |
PRSS2 | protease, serine, 2 (trypsin 2) |
PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
QPRT | quinolinate phosphoribosyltransferase |
SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SLPI | secretory leukocyte peptidase inhibitor |
SOX9 | SRY (sex determining region Y)-box 9 |
SPON1 | spondin 1, extracellular matrix protein |
ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
TCERG1 | transcription elongation regulator 1 |
TCF4 | transcription factor 4 |
TCL1A | T-cell leukemia/lymphoma 1A |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
TIMP3 | TIMP metallopeptidase inhibitor 3 |
UBE3C | ubiquitin protein ligase E3C |
VDAC1 | voltage-dependent anion channel 1 |
WT1 | Wilms tumor 1 |
Symbol | Name |
---|---|
AK4 | adenylate kinase 4 |
ANOS1 | anosmin 1 |
ASCL1 | achaete-scute family bHLH transcription factor 1 |
ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
BTG2 | BTG family, member 2 |
C7 | complement component 7 |
CBR3 | carbonyl reductase 3 |
CCL2 | chemokine (C-C motif) ligand 2 |
CDCA4 | cell division cycle associated 4 |
CDK1 | cyclin-dependent kinase 1 |
COPS7A | COP9 signalosome subunit 7A |
CRABP1 | cellular retinoic acid binding protein 1 |
CXCL10 | chemokine (C-X-C motif) ligand 10 |
CXCL9 | chemokine (C-X-C motif) ligand 9 |
CYB5A | cytochrome b5 type A (microsomal) |
DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DIO1 | deiodinase, iodothyronine, type I |
DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
ENO2 | enolase 2 (gamma, neuronal) |
FBP1 | fructose-1,6-bisphosphatase 1 |
FRY | furry homolog (Drosophila) |
GADD45B | growth arrest and DNA-damage-inducible, beta |
GPNMB | glycoprotein (transmembrane) nmb |
H1F0 | H1 histone family, member 0 |
H1FX | H1 histone family, member X |
HLA-C | major histocompatibility complex, class I, C |
HLA-F | major histocompatibility complex, class I, F |
IGFBP3 | insulin-like growth factor binding protein 3 |
IGFBP5 | insulin-like growth factor binding protein 5 |
IL6 | interleukin 6 |
INSIG1 | insulin induced gene 1 |
KDM5D | lysine (K)-specific demethylase 5D |
KLF10 | Kruppel-like factor 10 |
LGALS3 | lectin, galactoside-binding, soluble, 3 |
LUM | lumican |
MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
MSMB | microseminoprotein, beta- |
MSRB2 | methionine sulfoxide reductase B2 |
NEBL | nebulette |
NEFL | neurofilament, light polypeptide |
NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
NISCH | nischarin |
NPEPL1 | aminopeptidase-like 1 |
NREP | neuronal regeneration related protein |
P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
PPIC | peptidylprolyl isomerase C (cyclophilin C) |
RFC2 | replication factor C (activator 1) 2, 40kDa |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SCCPDH | saccharopine dehydrogenase (putative) |
SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
SFN | stratifin |
SIK1 | salt-inducible kinase 1 |
SOX4 | SRY (sex determining region Y)-box 4 |
SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
SPTSSA | serine palmitoyltransferase, small subunit A |
SYNGR1 | synaptogyrin 1 |
TACSTD2 | tumor-associated calcium signal transducer 2 |
TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) |
TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
WEE1 | WEE1 G2 checkpoint kinase |