BRD-K92571446_WZ-3105_HA1E_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-K92571446_WZ-3105_HA1E_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
BAG3 BCL2-associated athanogene 3
CD163 CD163 molecule
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CSTA cystatin A (stefin A)
DUSP4 dual specificity phosphatase 4
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FAM63A family with sequence similarity 63, member A
FBN2 fibrillin 2
GRAMD1C GRAM domain containing 1C
GSN gelsolin
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2BE histone cluster 1, H2be
HIST1H2BG histone cluster 1, H2bg
HIST1H2BK histone cluster 1, H2bk
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXB2 homeobox B2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
KRT13 keratin 13, type I
KRT19 keratin 19, type I
KRT23 keratin 23, type I
KRT6A keratin 6A, type II
LY6D lymphocyte antigen 6 complex, locus D
LYZ lysozyme
MAGEA4 melanoma antigen family A4
MMP12 matrix metallopeptidase 12
MYO6 myosin VI
MYOF myoferlin
PERP PERP, TP53 apoptosis effector
PI3 peptidase inhibitor 3, skin-derived
PLAC8 placenta-specific 8
PLBD1 phospholipase B domain containing 1
PPAP2B phosphatidic acid phosphatase type 2B
RHCG Rh family, C glycoprotein
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SCPEP1 serine carboxypeptidase 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SPRR2B small proline-rich protein 2B
SPRR3 small proline-rich protein 3
USP6NL USP6 N-terminal like

decreased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
C14ORF2 chromosome 14 open reading frame 2
CLEC2B C-type lectin domain family 2, member B
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CXCL12 chemokine (C-X-C motif) ligand 12
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
EIF5A eukaryotic translation initiation factor 5A
FN1 fibronectin 1
INHBA inhibin, beta A
INSIG1 insulin induced gene 1
LAPTM4B lysosomal protein transmembrane 4 beta
LYPLA1 lysophospholipase I
OXA1L oxidase (cytochrome c) assembly 1-like
PRDX2 peroxiredoxin 2
RNF167 ring finger protein 167
RPS11 ribosomal protein S11
SATB1 SATB homeobox 1
SMYD2 SET and MYND domain containing 2
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TCTA T-cell leukemia translocation altered
TFF3 trefoil factor 3 (intestinal)
THBS2 thrombospondin 2
TKT transketolase
TUBB6 tubulin, beta 6 class V
Funding