BRD-K92742972_2-({[2-(4-ethoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl}thio)-N-(2-furylmethyl)acetamide MLS-0052895.0001_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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33 genes differentially expressed following the BRD-K92742972_2-({[2-(4-ethoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl}thio)-N-(2-furylmethyl)acetamide MLS-0052895.0001_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDOB aldolase B, fructose-bisphosphate
BEX1 brain expressed, X-linked 1
CLC Charcot-Leyden crystal galectin
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
ELANE elastase, neutrophil expressed
EREG epiregulin
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
HOPX HOP homeobox
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP5 insulin-like growth factor binding protein 5
MMP9 matrix metallopeptidase 9
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
NCAM1 neural cell adhesion molecule 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
CCDC86 coiled-coil domain containing 86
CDC42 cell division cycle 42
CLTB clathrin, light chain B
CTTN cortactin
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
LYPLA1 lysophospholipase I
MORC4 MORC family CW-type zinc finger 4
OXA1L oxidase (cytochrome c) assembly 1-like
PROM1 prominin 1
REEP5 receptor accessory protein 5
RPL27A ribosomal protein L27a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
UBE3C ubiquitin protein ligase E3C
XPO7 exportin 7