Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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59 genes differentially expressed following the BRD-K93023739_IKK Inhibitor X_VCAP_6.0_h_6.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AHNAK | AHNAK nucleoprotein |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
CAST | calpastatin |
CCND2 | cyclin D2 |
CXCL9 | chemokine (C-X-C motif) ligand 9 |
DUSP22 | dual specificity phosphatase 22 |
FN1 | fibronectin 1 |
GPNMB | glycoprotein (transmembrane) nmb |
IGFBP5 | insulin-like growth factor binding protein 5 |
IL13RA1 | interleukin 13 receptor, alpha 1 |
JAG1 | jagged 1 |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MAN1A1 | mannosidase, alpha, class 1A, member 1 |
MEOX2 | mesenchyme homeobox 2 |
MPPED2 | metallophosphoesterase domain containing 2 |
NPTX2 | neuronal pentraxin II |
NRCAM | neuronal cell adhesion molecule |
PEG3 | paternally expressed 3 |
PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
RBP4 | retinol binding protein 4, plasma |
RGCC | regulator of cell cycle |
SCGB1D2 | secretoglobin, family 1D, member 2 |
SFRP4 | secreted frizzled-related protein 4 |
SOD2 | superoxide dismutase 2, mitochondrial |
SPON1 | spondin 1, extracellular matrix protein |
SST | somatostatin |
TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
TPD52L1 | tumor protein D52-like 1 |
ZFP36L2 | ZFP36 ring finger protein-like 2 |
Symbol | Name |
---|---|
BST2 | bone marrow stromal cell antigen 2 |
CLDN18 | claudin 18 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DLC1 | DLC1 Rho GTPase activating protein |
FLRT3 | fibronectin leucine rich transmembrane protein 3 |
GPRC5A | G protein-coupled receptor, class C, group 5, member A |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
IFI27 | interferon, alpha-inducible protein 27 |
IFI44 | interferon-induced protein 44 |
IFI44L | interferon-induced protein 44-like |
IFI6 | interferon, alpha-inducible protein 6 |
IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
IGFBP6 | insulin-like growth factor binding protein 6 |
ISG15 | ISG15 ubiquitin-like modifier |
LBH | limb bud and heart development |
MX1 | MX dynamin-like GTPase 1 |
OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
OASL | 2'-5'-oligoadenylate synthetase-like |
SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
USP18 | ubiquitin specific peptidase 18 |