| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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69 genes differentially expressed following the BRD-K93123848_RAF 265_A375_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ASPN | asporin |
| ASS1 | argininosuccinate synthase 1 |
| BMP4 | bone morphogenetic protein 4 |
| CBS | cystathionine-beta-synthase |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CFB | complement factor B |
| CHRDL1 | chordin-like 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 |
| EPRS | glutamyl-prolyl-tRNA synthetase |
| GARS | glycyl-tRNA synthetase |
| IGKC | immunoglobulin kappa constant |
| IGL | immunoglobulin lambda locus |
| IGLV2-23 | immunoglobulin lambda variable 2-23 |
| JCHAIN | joining chain of multimeric IgA and IgM |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
| MYH11 | myosin, heavy chain 11, smooth muscle |
| OLFM4 | olfactomedin 4 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PHGDH | phosphoglycerate dehydrogenase |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSPH | phosphoserine phosphatase |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| XPOT | exportin, tRNA |
| YARS | tyrosyl-tRNA synthetase |
| Symbol | Name |
|---|---|
| APP | amyloid beta (A4) precursor protein |
| ASPH | aspartate beta-hydroxylase |
| CD9 | CD9 molecule |
| CDC42 | cell division cycle 42 |
| CSTA | cystatin A (stefin A) |
| CTSZ | cathepsin Z |
| DSP | desmoplakin |
| EMP1 | epithelial membrane protein 1 |
| FABP7 | fatty acid binding protein 7, brain |
| FN1 | fibronectin 1 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HK2 | hexokinase 2 |
| HOPX | HOP homeobox |
| HOXB7 | homeobox B7 |
| IL1R2 | interleukin 1 receptor, type II |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KRT17 | keratin 17, type I |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 |
| MAP7 | microtubule-associated protein 7 |
| MSH6 | mutS homolog 6 |
| NRIP3 | nuclear receptor interacting protein 3 |
| PEG3 | paternally expressed 3 |
| PI3 | peptidase inhibitor 3, skin-derived |
| QPCT | glutaminyl-peptide cyclotransferase |
| S100A7 | S100 calcium binding protein A7 |
| S100A9 | S100 calcium binding protein A9 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SFN | stratifin |
| SOSTDC1 | sclerostin domain containing 1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPRR1A | small proline-rich protein 1A |
| SPRR1B | small proline-rich protein 1B |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TMEM97 | transmembrane protein 97 |
| TOB1 | transducer of ERBB2, 1 |
| XIST | X inactive specific transcript (non-protein coding) |
