| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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74 genes differentially expressed following the BRD-K93215584_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| CD44 | CD44 molecule (Indian blood group) |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 |
| EIF1B | eukaryotic translation initiation factor 1B |
| EPCAM | epithelial cell adhesion molecule |
| FADS1 | fatty acid desaturase 1 |
| FOSL1 | FOS-like antigen 1 |
| FTH1 | ferritin, heavy polypeptide 1 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IL6R | interleukin 6 receptor |
| IRS2 | insulin receptor substrate 2 |
| MDK | midkine (neurite growth-promoting factor 2) |
| MT1M | metallothionein 1M |
| NTS | neurotensin |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| RLF | rearranged L-myc fusion |
| RRAD | Ras-related associated with diabetes |
| S100P | S100 calcium binding protein P |
| SFN | stratifin |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SQLE | squalene epoxidase |
| SQSTM1 | sequestosome 1 |
| TFF3 | trefoil factor 3 (intestinal) |
| TOB2 | transducer of ERBB2, 2 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) |
| VEGFA | vascular endothelial growth factor A |
| VGLL4 | vestigial-like family member 4 |
| Symbol | Name |
|---|---|
| ALOX5 | arachidonate 5-lipoxygenase |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANXA2P2 | annexin A2 pseudogene 2 |
| BCHE | butyrylcholinesterase |
| CCNB2 | cyclin B2 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CLIC4 | chloride intracellular channel 4 |
| COL3A1 | collagen, type III, alpha 1 |
| CRYAB | crystallin, alpha B |
| CTGF | connective tissue growth factor |
| DPP4 | dipeptidyl-peptidase 4 |
| EMP1 | epithelial membrane protein 1 |
| ENO1 | enolase 1, (alpha) |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GRN | granulin |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial |
| MAP7 | microtubule-associated protein 7 |
| MXRA7 | matrix-remodelling associated 7 |
| NNMT | nicotinamide N-methyltransferase |
| NREP | neuronal regeneration related protein |
| PDIA6 | protein disulfide isomerase family A, member 6 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLS3 | plastin 3 |
| PON2 | paraoxonase 2 |
| PSPH | phosphoserine phosphatase |
| PTTG1 | pituitary tumor-transforming 1 |
| PXDN | peroxidasin |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SDC1 | syndecan 1 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| SPON1 | spondin 1, extracellular matrix protein |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TBC1D16 | TBC1 domain family, member 16 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TPM1 | tropomyosin 1 (alpha) |
| TSPAN12 | tetraspanin 12 |
| TXNDC9 | thioredoxin domain containing 9 |
| WWTR1 | WW domain containing transcription regulator 1 |
