BRD-K93229693_2-(2-methoxyphenyl)-N-{4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl}acetamide_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-K93229693_2-(2-methoxyphenyl)-N-{4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl}acetamide_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP12 A kinase (PRKA) anchor protein 12
ANKRD10 ankyrin repeat domain 10
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ATF3 activating transcription factor 3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IRS2 insulin receptor substrate 2
JUN jun proto-oncogene
KLF6 Kruppel-like factor 6
KYNU kynureninase
LPL lipoprotein lipase
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
NAMPT nicotinamide phosphoribosyltransferase
NFIL3 nuclear factor, interleukin 3 regulated
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
OPN3 opsin 3
PHGDH phosphoglycerate dehydrogenase
PHLDA1 pleckstrin homology-like domain, family A, member 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHOB ras homolog family member B
S100P S100 calcium binding protein P
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
TACC2 transforming, acidic coiled-coil containing protein 2
TRIB1 tribbles pseudokinase 1
TRIM16 tripartite motif containing 16
TXNRD1 thioredoxin reductase 1
VCAM1 vascular cell adhesion molecule 1
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CXCL10 chemokine (C-X-C motif) ligand 10
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EZR ezrin
FGFR3 fibroblast growth factor receptor 3
GNAS GNAS complex locus
GTF2A2 general transcription factor IIA, 2, 12kDa
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
PRKCD protein kinase C, delta
PROM1 prominin 1
RFTN1 raftlin, lipid raft linker 1
S100A9 S100 calcium binding protein A9
SDC2 syndecan 2
SH3BGRL SH3 domain binding glutamate-rich protein like
SPON1 spondin 1, extracellular matrix protein
SRSF1 serine/arginine-rich splicing factor 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIM22 tripartite motif containing 22
TSPAN13 tetraspanin 13
VCAN versican
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