BRD-K93229693_2-(2-methoxyphenyl)-N-{4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl}acetamide_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

37 genes differentially expressed following the BRD-K93229693_2-(2-methoxyphenyl)-N-{4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl}acetamide_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASNS asparagine synthetase (glutamine-hydrolyzing)
CCL2 chemokine (C-C motif) ligand 2
CES1 carboxylesterase 1
DDIT4 DNA-damage-inducible transcript 4
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
FAM129A family with sequence similarity 129, member A
GADD45B growth arrest and DNA-damage-inducible, beta
HSPA1A heat shock 70kDa protein 1A
IGFBP7 insulin-like growth factor binding protein 7
IGHD immunoglobulin heavy constant delta
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
METTL7A methyltransferase like 7A
MT1F metallothionein 1F
NREP neuronal regeneration related protein
POSTN periostin, osteoblast specific factor
RGS2 regulator of G-protein signaling 2
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
THBS2 thrombospondin 2
VCAN versican
ZBTB16 zinc finger and BTB domain containing 16
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
AMD1 adenosylmethionine decarboxylase 1
ANGPT1 angiopoietin 1
CD47 CD47 molecule
CDC20 cell division cycle 20
CSRP1 cysteine and glycine-rich protein 1
CTSH cathepsin H
GMPR guanosine monophosphate reductase
GUSBP3 glucuronidase, beta pseudogene 3
ITGA6 integrin, alpha 6
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPM4 tropomyosin 4
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