| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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124 genes differentially expressed following the BRD-K93480852_-666_NPC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ASPN | asporin |
| ASS1 | argininosuccinate synthase 1 |
| ATM | ATM serine/threonine kinase |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BMP4 | bone morphogenetic protein 4 |
| CD24 | CD24 molecule |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CD9 | CD9 molecule |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLDN3 | claudin 3 |
| CPA3 | carboxypeptidase A3 (mast cell) |
| CST6 | cystatin E/M |
| CSTA | cystatin A (stefin A) |
| DDC | dopa decarboxylase (aromatic L-amino acid decarboxylase) |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 |
| EPCAM | epithelial cell adhesion molecule |
| ESRP1 | epithelial splicing regulatory protein 1 |
| F11R | F11 receptor |
| FAM129A | family with sequence similarity 129, member A |
| FAM60A | family with sequence similarity 60, member A |
| GRB10 | growth factor receptor-bound protein 10 |
| GRB7 | growth factor receptor-bound protein 7 |
| HIST1H2BG | histone cluster 1, H2bg |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| IPO13 | importin 13 |
| JCHAIN | joining chain of multimeric IgA and IgM |
| JUP | junction plakoglobin |
| LCN2 | lipocalin 2 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
| MMP7 | matrix metallopeptidase 7 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PERP | PERP, TP53 apoptosis effector |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
| POSTN | periostin, osteoblast specific factor |
| PPL | periplakin |
| PTPRK | protein tyrosine phosphatase, receptor type, K |
| QPCT | glutaminyl-peptide cyclotransferase |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase |
| S100A8 | S100 calcium binding protein A8 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SFRP4 | secreted frizzled-related protein 4 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) |
| SULF1 | sulfatase 1 |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| VSNL1 | visinin-like 1 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| Symbol | Name |
|---|---|
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ALCAM | activated leukocyte cell adhesion molecule |
| AMD1 | adenosylmethionine decarboxylase 1 |
| ANXA6 | annexin A6 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa |
| AXL | AXL receptor tyrosine kinase |
| BST2 | bone marrow stromal cell antigen 2 |
| CALD1 | caldesmon 1 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CLU | clusterin |
| COL4A1 | collagen, type IV, alpha 1 |
| COL4A2 | collagen, type IV, alpha 2 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| CSRP1 | cysteine and glycine-rich protein 1 |
| CTGF | connective tissue growth factor |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DUSP4 | dual specificity phosphatase 4 |
| EBNA1BP2 | EBNA1 binding protein 2 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FASTKD5 | FAST kinase domains 5 |
| FLNA | filamin A, alpha |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IL13RA2 | interleukin 13 receptor, alpha 2 |
| KPNB1 | karyopherin (importin) beta 1 |
| KRT7 | keratin 7, type II |
| LAMB1 | laminin, beta 1 |
| LEPR | leptin receptor |
| MAN2B1 | mannosidase, alpha, class 2B, member 1 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MRPL12 | mitochondrial ribosomal protein L12 |
| MRPS16 | mitochondrial ribosomal protein S16 |
| MYCBP | MYC binding protein |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 |
| NUP62 | nucleoporin 62kDa |
| ODC1 | ornithine decarboxylase 1 |
| PALLD | palladin, cytoskeletal associated protein |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa |
| PRDX4 | peroxiredoxin 4 |
| PRMT1 | protein arginine methyltransferase 1 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 |
| RAE1 | ribonucleic acid export 1 |
| RBM25 | RNA binding motif protein 25 |
| RHOB | ras homolog family member B |
| RPS11 | ribosomal protein S11 |
| SACS | sacsin molecular chaperone |
| SCRG1 | stimulator of chondrogenesis 1 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SRGN | serglycin |
| TFAM | transcription factor A, mitochondrial |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TSPAN4 | tetraspanin 4 |
| TYMS | thymidylate synthetase |
