| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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162 genes differentially expressed following the BRD-K93725829_ERK inhibitor 11e_A375_24.0_h_0.5_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACKR3 | atypical chemokine receptor 3 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADIRF | adipogenesis regulatory factor |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| ANXA4 | annexin A4 |
| APOD | apolipoprotein D |
| BLNK | B-cell linker |
| C14ORF132 | chromosome 14 open reading frame 132 |
| CADM1 | cell adhesion molecule 1 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCNG2 | cyclin G2 |
| CD9 | CD9 molecule |
| CNN1 | calponin 1, basic, smooth muscle |
| COLEC12 | collectin sub-family member 12 |
| CRIP2 | cysteine-rich protein 2 |
| CRYAB | crystallin, alpha B |
| DDR1 | discoidin domain receptor tyrosine kinase 1 |
| DES | desmin |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| EFNA1 | ephrin-A1 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| FAM63A | family with sequence similarity 63, member A |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| GAS1 | growth arrest-specific 1 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GPM6A | glycoprotein M6A |
| GPNMB | glycoprotein (transmembrane) nmb |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| IFI44L | interferon-induced protein 44-like |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| IRF9 | interferon regulatory factor 9 |
| ISG15 | ISG15 ubiquitin-like modifier |
| LAMP2 | lysosomal-associated membrane protein 2 |
| LMOD1 | leiomodin 1 (smooth muscle) |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| MAGED2 | melanoma antigen family D2 |
| MATN2 | matrilin 2 |
| METRN | meteorin, glial cell differentiation regulator |
| MMP2 | matrix metallopeptidase 2 |
| MTMR11 | myotubularin related protein 11 |
| MVP | major vault protein |
| NDRG2 | NDRG family member 2 |
| NES | nestin |
| NRCAM | neuronal cell adhesion molecule |
| NREP | neuronal regeneration related protein |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PEG3 | paternally expressed 3 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIPOX | pipecolic acid oxidase |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLP1 | proteolipid protein 1 |
| PPAP2A | phosphatidic acid phosphatase type 2A |
| PRAF2 | PRA1 domain family, member 2 |
| PRSS23 | protease, serine, 23 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PTN | pleiotrophin |
| RBP1 | retinol binding protein 1, cellular |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| S100A4 | S100 calcium binding protein A4 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCRG1 | stimulator of chondrogenesis 1 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like |
| SLC35E2B | solute carrier family 35, member E2B |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SOX2 | SRY (sex determining region Y)-box 2 |
| SPATA20 | spermatogenesis associated 20 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| SYT11 | synaptotagmin XI |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TPD52L1 | tumor protein D52-like 1 |
| TPP1 | tripeptidyl peptidase I |
| TRIM2 | tripartite motif containing 2 |
| TRIM22 | tripartite motif containing 22 |
| TSPAN31 | tetraspanin 31 |
| TUBA1A | tubulin, alpha 1a |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| VGLL4 | vestigial-like family member 4 |
| ZMAT3 | zinc finger, matrin-type 3 |
| Symbol | Name |
|---|---|
| ACTN1 | actinin, alpha 1 |
| CCDC86 | coiled-coil domain containing 86 |
| CCND1 | cyclin D1 |
| CCNE2 | cyclin E2 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDC25A | cell division cycle 25A |
| CDC6 | cell division cycle 6 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CLTB | clathrin, light chain B |
| COL4A1 | collagen, type IV, alpha 1 |
| COL4A2 | collagen, type IV, alpha 2 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DKC1 | dyskeratosis congenita 1, dyskerin |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| DUSP4 | dual specificity phosphatase 4 |
| EIF5A | eukaryotic translation initiation factor 5A |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| EXO1 | exonuclease 1 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FEN1 | flap structure-specific endonuclease 1 |
| FOSL1 | FOS-like antigen 1 |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GAL | galanin/GMAP prepropeptide |
| GARS | glycyl-tRNA synthetase |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| HES1 | hes family bHLH transcription factor 1 |
| HMGA2 | high mobility group AT-hook 2 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IER3 | immediate early response 3 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| INHBA | inhibin, beta A |
| KRT18 | keratin 18, type I |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM7 | minichromosome maintenance complex component 7 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MMP9 | matrix metallopeptidase 9 |
| MOK | MOK protein kinase |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
| ODC1 | ornithine decarboxylase 1 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PI3 | peptidase inhibitor 3, skin-derived |
| PLAUR | plasminogen activator, urokinase receptor |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PNP | purine nucleoside phosphorylase |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PPIF | peptidylprolyl isomerase F |
| PTGES | prostaglandin E synthase |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RUNX3 | runt-related transcription factor 3 |
| S100A9 | S100 calcium binding protein A9 |
| S100P | S100 calcium binding protein P |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 |
| SLC43A3 | solute carrier family 43, member 3 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| STC1 | stanniocalcin 1 |
| STX1A | syntaxin 1A (brain) |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TMEM2 | transmembrane protein 2 |
| TMEM97 | transmembrane protein 97 |
| TPM1 | tropomyosin 1 (alpha) |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
