| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
90 genes differentially expressed following the BRD-K93725829_ERK inhibitor 11e_SW620_6.0_h_0.5_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| CLEC2B | C-type lectin domain family 2, member B |
| CP | ceruloplasmin (ferroxidase) |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B |
| GSPT2 | G1 to S phase transition 2 |
| GSTT1 | glutathione S-transferase theta 1 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IGL | immunoglobulin lambda locus |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| ITGB1BP1 | integrin beta 1 binding protein 1 |
| JCHAIN | joining chain of multimeric IgA and IgM |
| MEF2C | myocyte enhancer factor 2C |
| NARFL | nuclear prelamin A recognition factor-like |
| NMU | neuromedin U |
| ORC1 | origin recognition complex, subunit 1 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated |
| PDGFD | platelet derived growth factor D |
| PEG10 | paternally expressed 10 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 |
| RAD51AP1 | RAD51 associated protein 1 |
| RTN2 | reticulon 2 |
| S100A8 | S100 calcium binding protein A8 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| STS | steroid sulfatase (microsomal), isozyme S |
| TRIM2 | tripartite motif containing 2 |
| UGP2 | UDP-glucose pyrophosphorylase 2 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| WDR7 | WD repeat domain 7 |
| Symbol | Name |
|---|---|
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ANPEP | alanyl (membrane) aminopeptidase |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYBA | cytochrome b-245, alpha polypeptide |
| CYTL1 | cytokine-like 1 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| EMP1 | epithelial membrane protein 1 |
| ERLIN1 | ER lipid raft associated 1 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FAM46A | family with sequence similarity 46, member A |
| FOSL1 | FOS-like antigen 1 |
| G6PD | glucose-6-phosphate dehydrogenase |
| GATA3 | GATA binding protein 3 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 |
| GPC3 | glypican 3 |
| H2AFX | H2A histone family, member X |
| HES1 | hes family bHLH transcription factor 1 |
| HOMER1 | homer scaffolding protein 1 |
| IER3 | immediate early response 3 |
| IGF1R | insulin-like growth factor 1 receptor |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| INPP1 | inositol polyphosphate-1-phosphatase |
| KLF6 | Kruppel-like factor 6 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) |
| LMNA | lamin A/C |
| MALL | mal, T-cell differentiation protein-like |
| MAP2K3 | mitogen-activated protein kinase kinase 3 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MGP | matrix Gla protein |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| ODC1 | ornithine decarboxylase 1 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLAC8 | placenta-specific 8 |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PRR7 | proline rich 7 (synaptic) |
| PRSS3 | protease, serine, 3 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 |
| S100A11 | S100 calcium binding protein A11 |
| SORD | sorbitol dehydrogenase |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| SRPX | sushi-repeat containing protein, X-linked |
| SVIL | supervillin |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TSPAN4 | tetraspanin 4 |
| UBE2S | ubiquitin-conjugating enzyme E2S |
