BRD-K93747373_HG-5-113-01_HA1E_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K93747373_HG-5-113-01_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
FAS Fas cell surface death receptor
FBN2 fibrillin 2
GATA3 GATA binding protein 3
GNLY granulysin
GSTZ1 glutathione S-transferase zeta 1
HIST1H2BK histone cluster 1, H2bk
HOPX HOP homeobox
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV3-20 immunoglobulin kappa variable 3-20
JADE2 jade family PHD finger 2
KIAA0355 KIAA0355
KRT6B keratin 6B, type II
NELL2 NEL-like 2 (chicken)
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
POSTN periostin, osteoblast specific factor
RGS2 regulator of G-protein signaling 2
SIRT3 sirtuin 3
SLAMF7 SLAM family member 7

decreased expression

Symbol Name
ACSL3 acyl-CoA synthetase long-chain family member 3
ADAM12 ADAM metallopeptidase domain 12
AKAP12 A kinase (PRKA) anchor protein 12
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
C3 complement component 3
CADM1 cell adhesion molecule 1
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CD24 CD24 molecule
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
DACT1 dishevelled-binding antagonist of beta-catenin 1
DHCR24 24-dehydrocholesterol reductase
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
EDN1 endothelin 1
EIF5 eukaryotic translation initiation factor 5
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FERMT2 fermitin family member 2
GREB1 growth regulation by estrogen in breast cancer 1
HSPA8 heat shock 70kDa protein 8
ICAM1 intercellular adhesion molecule 1
IGFBP5 insulin-like growth factor binding protein 5
INSIG1 insulin induced gene 1
KLF4 Kruppel-like factor 4 (gut)
LCN2 lipocalin 2
MAPK13 mitogen-activated protein kinase 13
MEIS1 Meis homeobox 1
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MSLN mesothelin
MSMO1 methylsterol monooxygenase 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NPR3 natriuretic peptide receptor 3
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PFKP phosphofructokinase, platelet
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
QPRT quinolinate phosphoribosyltransferase
RRM2 ribonucleotide reductase M2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
TFRC transferrin receptor
TGFBI transforming growth factor, beta-induced, 68kDa
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNS3 tensin 3
TUBB6 tubulin, beta 6 class V
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VCL vinculin
VLDLR very low density lipoprotein receptor
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