BRD-K93788137_PF-431396_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K93788137_PF-431396_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ADRB2 adrenoceptor beta 2, surface
CD36 CD36 molecule (thrombospondin receptor)
CXCR4 chemokine (C-X-C motif) receptor 4
DCXR dicarbonyl/L-xylulose reductase
DLK1 delta-like 1 homolog (Drosophila)
DUSP1 dual specificity phosphatase 1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FGFR3 fibroblast growth factor receptor 3
IFI27 interferon, alpha-inducible protein 27
JUN jun proto-oncogene
KRT5 keratin 5, type II
LEF1 lymphoid enhancer-binding factor 1
MME membrane metallo-endopeptidase
NDRG1 N-myc downstream regulated 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
RCN1 reticulocalbin 1, EF-hand calcium binding domain
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPON2 spondin 2, extracellular matrix protein
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF3 trefoil factor 3 (intestinal)
TUSC3 tumor suppressor candidate 3
WFDC1 WAP four-disulfide core domain 1

decreased expression

Symbol Name
AURKA aurora kinase A
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
OPN3 opsin 3
PLA2G16 phospholipase A2, group XVI
RBPMS RNA binding protein with multiple splicing
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
VGLL1 vestigial-like family member 1
Funding