BRD-K93788137_PF-431396_HT29_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K93788137_PF-431396_HT29_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOD apolipoprotein D
BHLHE41 basic helix-loop-helix family, member e41
C10ORF10 chromosome 10 open reading frame 10
CD47 CD47 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFB complement factor B
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHPT1 choline phosphotransferase 1
CLU clusterin
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DLK1 delta-like 1 homolog (Drosophila)
EDN1 endothelin 1
EFNA1 ephrin-A1
FGF13 fibroblast growth factor 13
FGFR3 fibroblast growth factor receptor 3
FOXO4 forkhead box O4
GDF15 growth differentiation factor 15
GLUL glutamate-ammonia ligase
HIST1H2BD histone cluster 1, H2bd
IL17RB interleukin 17 receptor B
JUP junction plakoglobin
KRT7 keratin 7, type II
LCN2 lipocalin 2
MGP matrix Gla protein
MVP major vault protein
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PBX3 pre-B-cell leukemia homeobox 3
PDZK1IP1 PDZK1 interacting protein 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRK protein tyrosine phosphatase, receptor type, K
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAB13 RAB13, member RAS oncogene family
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SOX4 SRY (sex determining region Y)-box 4
SOX9 SRY (sex determining region Y)-box 9
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOX3 TOX high mobility group box family member 3
TSC22D1 TSC22 domain family, member 1
TSPYL5 TSPY-like 5
TST thiosulfate sulfurtransferase (rhodanese)
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ANO1 anoctamin 1, calcium activated chloride channel
COL4A2 collagen, type IV, alpha 2
COL5A2 collagen, type V, alpha 2
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EXOSC4 exosome component 4
FOSL1 FOS-like antigen 1
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HBB hemoglobin, beta
HCAR3 hydroxycarboxylic acid receptor 3
HOPX HOP homeobox
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
ODC1 ornithine decarboxylase 1
RGS5 regulator of G-protein signaling 5
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
STXBP6 syntaxin binding protein 6 (amisyn)
THBS2 thrombospondin 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
Funding