BRD-K93788137_PF-431396_SKBR3_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

82 genes differentially expressed following the BRD-K93788137_PF-431396_SKBR3_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
ALCAM activated leukocyte cell adhesion molecule
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ASRGL1 asparaginase like 1
ATF3 activating transcription factor 3
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CSTA cystatin A (stefin A)
CYR61 cysteine-rich, angiogenic inducer, 61
DUSP2 dual specificity phosphatase 2
EZR ezrin
FASTKD5 FAST kinase domains 5
FOLR1 folate receptor 1 (adult)
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45B growth arrest and DNA-damage-inducible, beta
GREB1 growth regulation by estrogen in breast cancer 1
KLF10 Kruppel-like factor 10
KYNU kynureninase
MAOB monoamine oxidase B
MSLN mesothelin
NFIL3 nuclear factor, interleukin 3 regulated
NKX2-1 NK2 homeobox 1
NLGN4X neuroligin 4, X-linked
NPTX2 neuronal pentraxin II
NR4A3 nuclear receptor subfamily 4, group A, member 3
ODC1 ornithine decarboxylase 1
PCP4 Purkinje cell protein 4
PDZK1 PDZ domain containing 1
PDZK1IP1 PDZK1 interacting protein 1
PEX11A peroxisomal biogenesis factor 11 alpha
PLAC8 placenta-specific 8
PON2 paraoxonase 2
PRNP prion protein
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAI2 retinoic acid induced 2
RPS4Y1 ribosomal protein S4, Y-linked 1
RRAS2 related RAS viral (r-ras) oncogene homolog 2
S100A10 S100 calcium binding protein A10
SCGB1D2 secretoglobin, family 1D, member 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SGK1 serum/glucocorticoid regulated kinase 1
SIK1 salt-inducible kinase 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SNX11 sorting nexin 11
SPON1 spondin 1, extracellular matrix protein
TFF1 trefoil factor 1
TFPI2 tissue factor pathway inhibitor 2
TOX thymocyte selection-associated high mobility group box
WFDC2 WAP four-disulfide core domain 2
ZNF185 zinc finger protein 185 (LIM domain)

decreased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
AURKA aurora kinase A
AUTS2 autism susceptibility candidate 2
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD44 CD44 molecule (Indian blood group)
CD9 CD9 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CHIC2 cysteine-rich hydrophobic domain 2
CLU clusterin
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
EPAS1 endothelial PAS domain protein 1
FABP4 fatty acid binding protein 4, adipocyte
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GPM6B glycoprotein M6B
IGFBP4 insulin-like growth factor binding protein 4
IGFBP7 insulin-like growth factor binding protein 7
IGL immunoglobulin lambda locus
KIAA0355 KIAA0355
LTF lactotransferrin
NUP62 nucleoporin 62kDa
RGS5 regulator of G-protein signaling 5
S100A9 S100 calcium binding protein A9
SRGN serglycin
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TDO2 tryptophan 2,3-dioxygenase
TRPS1 trichorhinophalangeal syndrome I
ZIC1 Zic family member 1
ZNF22 zinc finger protein 22
Funding