| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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186 genes differentially expressed following the BRD-K94012289_OSI-027_HME1_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ADD3 | adducin 3 (gamma) |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANKRD36B | ankyrin repeat domain 36B |
| ANXA1 | annexin A1 |
| ANXA4 | annexin A4 |
| APOD | apolipoprotein D |
| ATP9A | ATPase, class II, type 9A |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| C6ORF48 | chromosome 6 open reading frame 48 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CREBL2 | cAMP responsive element binding protein-like 2 |
| CSTA | cystatin A (stefin A) |
| CTBP2 | C-terminal binding protein 2 |
| CTSK | cathepsin K |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| DUSP4 | dual specificity phosphatase 4 |
| EGFR | epidermal growth factor receptor |
| EIF3G | eukaryotic translation initiation factor 3, subunit G |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| ETHE1 | ethylmalonic encephalopathy 1 |
| FAM60A | family with sequence similarity 60, member A |
| FTH1 | ferritin, heavy polypeptide 1 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 |
| GLTSCR2 | glioma tumor suppressor candidate region gene 2 |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| GRN | granulin |
| GSN | gelsolin |
| HDAC9 | histone deacetylase 9 |
| HIST3H2A | histone cluster 3, H2a |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| IL1B | interleukin 1, beta |
| IRS2 | insulin receptor substrate 2 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
| LAMA3 | laminin, alpha 3 |
| LAMC2 | laminin, gamma 2 |
| LETMD1 | LETM1 domain containing 1 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 |
| LMOD1 | leiomodin 1 (smooth muscle) |
| LXN | latexin |
| LY75 | lymphocyte antigen 75 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP7 | microtubule-associated protein 7 |
| MFAP5 | microfibrillar associated protein 5 |
| MMP1 | matrix metallopeptidase 1 |
| MMP12 | matrix metallopeptidase 12 |
| MTSS1 | metastasis suppressor 1 |
| NBR1 | neighbor of BRCA1 gene 1 |
| NPC1 | Niemann-Pick disease, type C1 |
| PDGFD | platelet derived growth factor D |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 |
| PLCB4 | phospholipase C, beta 4 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa |
| PRAME | preferentially expressed antigen in melanoma |
| PTCH1 | patched 1 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| REG1A | regenerating islet-derived 1 alpha |
| RPL31 | ribosomal protein L31 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCG5 | secretogranin V |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| SERINC1 | serine incorporator 1 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SFRP4 | secreted frizzled-related protein 4 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SPG11 | spastic paraplegia 11 (autosomal recessive) |
| SQSTM1 | sequestosome 1 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TNS3 | tensin 3 |
| TPD52L1 | tumor protein D52-like 1 |
| TRD | T cell receptor delta locus |
| VAT1 | vesicle amine transport 1 |
| VNN1 | vanin 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| ZNF277 | zinc finger protein 277 |
| ZNF586 | zinc finger protein 586 |
| ZNF91 | zinc finger protein 91 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ABAT | 4-aminobutyrate aminotransferase |
| AQP3 | aquaporin 3 (Gill blood group) |
| ASF1B | anti-silencing function 1B histone chaperone |
| ATAD2 | ATPase family, AAA domain containing 2 |
| AURKA | aurora kinase A |
| BIRC5 | baculoviral IAP repeat containing 5 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CALR | calreticulin |
| CCNA2 | cyclin A2 |
| CCNF | cyclin F |
| CDCA3 | cell division cycle associated 3 |
| CDCA8 | cell division cycle associated 8 |
| CDK1 | cyclin-dependent kinase 1 |
| CENPA | centromere protein A |
| CIT | citron rho-interacting serine/threonine kinase |
| CKAP2 | cytoskeleton associated protein 2 |
| CKS1B | CDC28 protein kinase regulatory subunit 1B |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| CYTL1 | cytokine-like 1 |
| DBF4 | DBF4 zinc finger |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DEPDC1 | DEP domain containing 1 |
| DHCR24 | 24-dehydrocholesterol reductase |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 |
| ELAVL1 | ELAV like RNA binding protein 1 |
| ELOVL6 | ELOVL fatty acid elongase 6 |
| EMP2 | epithelial membrane protein 2 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FEN1 | flap structure-specific endonuclease 1 |
| FOXM1 | forkhead box M1 |
| GATA3 | GATA binding protein 3 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GTSE1 | G-2 and S-phase expressed 1 |
| H2AFX | H2A histone family, member X |
| HAT1 | histone acetyltransferase 1 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HIST1H4C | histone cluster 1, H4c |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| INSIG1 | insulin induced gene 1 |
| KIAA0101 | KIAA0101 |
| KIF18B | kinesin family member 18B |
| KIF20A | kinesin family member 20A |
| KRT23 | keratin 23, type I |
| LMNB1 | lamin B1 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM4 | minichromosome maintenance complex component 4 |
| MCM5 | minichromosome maintenance complex component 5 |
| MELK | maternal embryonic leucine zipper kinase |
| MKI67 | marker of proliferation Ki-67 |
| MSMO1 | methylsterol monooxygenase 1 |
| MYCBP | MYC binding protein |
| NCAPG2 | non-SMC condensin II complex, subunit G2 |
| NCAPH | non-SMC condensin I complex, subunit H |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NET1 | neuroepithelial cell transforming 1 |
| NPY | neuropeptide Y |
| NPY1R | neuropeptide Y receptor Y1 |
| PARP2 | poly (ADP-ribose) polymerase 2 |
| PBK | PDZ binding kinase |
| PCNA | proliferating cell nuclear antigen |
| PHGDH | phosphoglycerate dehydrogenase |
| PLK1 | polo-like kinase 1 |
| PRC1 | protein regulator of cytokinesis 1 |
| RACGAP1 | Rac GTPase activating protein 1 |
| RCC1 | regulator of chromosome condensation 1 |
| RPA3 | replication protein A3, 14kDa |
| RRM2 | ribonucleotide reductase M2 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SDHC | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SPTSSA | serine palmitoyltransferase, small subunit A |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TAGLN2 | transgelin 2 |
| TBL1X | transducin (beta)-like 1X-linked |
| TIMELESS | timeless circadian clock |
| TMPO | thymopoietin |
| TNC | tenascin C |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TPX2 | TPX2, microtubule-associated |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TSPAN8 | tetraspanin 8 |
| TYMS | thymidylate synthetase |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| UNC13B | unc-13 homolog B (C. elegans) |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
| ZWINT | ZW10 interacting kinetochore protein |
