Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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75 genes differentially expressed following the BRD-K94012289_OSI-027_LNCAP_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
C1R | complement component 1, r subcomponent |
C7 | complement component 7 |
CCNG2 | cyclin G2 |
CFD | complement factor D (adipsin) |
CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
DEPTOR | DEP domain containing MTOR-interacting protein |
EIF5A | eukaryotic translation initiation factor 5A |
FAM46A | family with sequence similarity 46, member A |
FZD7 | frizzled class receptor 7 |
GAL | galanin/GMAP prepropeptide |
GBP2 | guanylate binding protein 2, interferon-inducible |
GPM6B | glycoprotein M6B |
HBP1 | HMG-box transcription factor 1 |
KIAA0753 | KIAA0753 |
LMBRD1 | LMBR1 domain containing 1 |
ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial |
MXI1 | MAX interactor 1, dimerization protein |
NFIB | nuclear factor I/B |
PBX3 | pre-B-cell leukemia homeobox 3 |
PCNA | proliferating cell nuclear antigen |
PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
RAB13 | RAB13, member RAS oncogene family |
RABGAP1L | RAB GTPase activating protein 1-like |
SFRP1 | secreted frizzled-related protein 1 |
SOX4 | SRY (sex determining region Y)-box 4 |
TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
TPR | translocated promoter region, nuclear basket protein |
TRIM2 | tripartite motif containing 2 |
TXNIP | thioredoxin interacting protein |
VCAN | versican |
WISP2 | WNT1 inducible signaling pathway protein 2 |
YBX3 | Y box binding protein 3 |
ZNF292 | zinc finger protein 292 |
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AGR2 | anterior gradient 2 |
AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
AMD1 | adenosylmethionine decarboxylase 1 |
CA12 | carbonic anhydrase XII |
CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CLDN4 | claudin 4 |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
DDIT4 | DNA-damage-inducible transcript 4 |
DEFB1 | defensin, beta 1 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
EMX2 | empty spiracles homeobox 2 |
EZR | ezrin |
GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
HSPA2 | heat shock 70kDa protein 2 |
HSPB8 | heat shock 22kDa protein 8 |
LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
MAT2A | methionine adenosyltransferase II, alpha |
MME | membrane metallo-endopeptidase |
MMP11 | matrix metallopeptidase 11 |
NEBL | nebulette |
PFN2 | profilin 2 |
PIR | pirin (iron-binding nuclear protein) |
PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
PPP1R16B | protein phosphatase 1, regulatory subunit 16B |
PSAT1 | phosphoserine aminotransferase 1 |
PTGDS | prostaglandin D2 synthase 21kDa (brain) |
RGCC | regulator of cell cycle |
RGS1 | regulator of G-protein signaling 1 |
RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
SCML1 | sex comb on midleg-like 1 (Drosophila) |
SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
SNAP25 | synaptosomal-associated protein, 25kDa |
SPP1 | secreted phosphoprotein 1 |
STC1 | stanniocalcin 1 |
TUBB2A | tubulin, beta 2A class IIa |