Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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100 genes differentially expressed following the BRD-K94012289_OSI-027_MCF10A_3_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACKR1 | atypical chemokine receptor 1 (Duffy blood group) |
AHNAK2 | AHNAK nucleoprotein 2 |
ALCAM | activated leukocyte cell adhesion molecule |
AP1S2 | adaptor-related protein complex 1, sigma 2 subunit |
AUTS2 | autism susceptibility candidate 2 |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
CCNG2 | cyclin G2 |
CD36 | CD36 molecule (thrombospondin receptor) |
CD44 | CD44 molecule (Indian blood group) |
CD59 | CD59 molecule, complement regulatory protein |
CERS6 | ceramide synthase 6 |
CHIC2 | cysteine-rich hydrophobic domain 2 |
CLU | clusterin |
COL4A6 | collagen, type IV, alpha 6 |
CREB1 | cAMP responsive element binding protein 1 |
CXADR | coxsackie virus and adenovirus receptor |
CYTH1 | cytohesin 1 |
DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
DPYSL2 | dihydropyrimidinase-like 2 |
EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
EGFR | epidermal growth factor receptor |
ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
ETV1 | ets variant 1 |
F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
GPM6B | glycoprotein M6B |
GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
HBP1 | HMG-box transcription factor 1 |
HMGA1 | high mobility group AT-hook 1 |
IGFBP6 | insulin-like growth factor binding protein 6 |
INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa |
LAMB3 | laminin, beta 3 |
MET | MET proto-oncogene, receptor tyrosine kinase |
MGLL | monoglyceride lipase |
NAV2 | neuron navigator 2 |
NFIB | nuclear factor I/B |
NUMA1 | nuclear mitotic apparatus protein 1 |
OLFM1 | olfactomedin 1 |
PFKL | phosphofructokinase, liver |
PLXNB2 | plexin B2 |
PNMA2 | paraneoplastic Ma antigen 2 |
PPAP2C | phosphatidic acid phosphatase type 2C |
PSAP | prosaposin |
SFRP1 | secreted frizzled-related protein 1 |
SKAP2 | src kinase associated phosphoprotein 2 |
SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 |
SLC38A1 | solute carrier family 38, member 1 |
SOX4 | SRY (sex determining region Y)-box 4 |
SOX9 | SRY (sex determining region Y)-box 9 |
SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
SRPX | sushi-repeat containing protein, X-linked |
TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
TNIP1 | TNFAIP3 interacting protein 1 |
TSC22D3 | TSC22 domain family, member 3 |
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ADO | 2-aminoethanethiol (cysteamine) dioxygenase |
AKR1C3 | aldo-keto reductase family 1, member C3 |
APOC1 | apolipoprotein C-I |
APOE | apolipoprotein E |
CCL4 | chemokine (C-C motif) ligand 4 |
CDC25A | cell division cycle 25A |
CHD7 | chromodomain helicase DNA binding protein 7 |
COG2 | component of oligomeric golgi complex 2 |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
EGR2 | early growth response 2 |
ESR1 | estrogen receptor 1 |
HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 |
HSPA1A | heat shock 70kDa protein 1A |
IGKV1-5 | immunoglobulin kappa variable 1-5 |
IGL | immunoglobulin lambda locus |
IL1RN | interleukin 1 receptor antagonist |
JMJD6 | jumonji domain containing 6 |
LAPTM4B | lysosomal protein transmembrane 4 beta |
LEF1 | lymphoid enhancer-binding factor 1 |
MCAM | melanoma cell adhesion molecule |
MMP9 | matrix metallopeptidase 9 |
MUC4 | mucin 4, cell surface associated |
MXRA7 | matrix-remodelling associated 7 |
MYRF | myelin regulatory factor |
NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
NEB | nebulin |
NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit |
PRPF4 | pre-mRNA processing factor 4 |
RAP2C | RAP2C, member of RAS oncogene family |
RGCC | regulator of cell cycle |
RGS1 | regulator of G-protein signaling 1 |
RGS2 | regulator of G-protein signaling 2 |
RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
S100A10 | S100 calcium binding protein A10 |
S100A8 | S100 calcium binding protein A8 |
SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
SCML1 | sex comb on midleg-like 1 (Drosophila) |
SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
SPAG4 | sperm associated antigen 4 |
TNNC1 | troponin C type 1 (slow) |
WT1 | Wilms tumor 1 |
XBP1 | X-box binding protein 1 |