Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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50 genes differentially expressed following the BRD-K94012289_OSI-027_MDAMB231_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
CD59 | CD59 molecule, complement regulatory protein |
CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CTSA | cathepsin A |
DOK5 | docking protein 5 |
FABP4 | fatty acid binding protein 4, adipocyte |
GPX4 | glutathione peroxidase 4 |
GSN | gelsolin |
IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
ITGAV | integrin, alpha V |
JAG1 | jagged 1 |
KLHL24 | kelch-like family member 24 |
KRT23 | keratin 23, type I |
MDK | midkine (neurite growth-promoting factor 2) |
MMD | monocyte to macrophage differentiation-associated |
NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
RB1CC1 | RB1-inducible coiled-coil 1 |
RTN2 | reticulon 2 |
SDCBP | syndecan binding protein (syntenin) |
SNAI2 | snail family zinc finger 2 |
SQSTM1 | sequestosome 1 |
SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 |
TCF7 | transcription factor 7 (T-cell specific, HMG-box) |
TFPI2 | tissue factor pathway inhibitor 2 |
TPP1 | tripeptidyl peptidase I |
WT1 | Wilms tumor 1 |
ZFAND5 | zinc finger, AN1-type domain 5 |
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
CCND2 | cyclin D2 |
CDC25A | cell division cycle 25A |
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
FEN1 | flap structure-specific endonuclease 1 |
GINS2 | GINS complex subunit 2 (Psf2 homolog) |
GPD1L | glycerol-3-phosphate dehydrogenase 1-like |
GRB14 | growth factor receptor-bound protein 14 |
H2AFX | H2A histone family, member X |
HSPA4L | heat shock 70kDa protein 4-like |
ICMT | isoprenylcysteine carboxyl methyltransferase |
IGHM | immunoglobulin heavy constant mu |
IGKV1-5 | immunoglobulin kappa variable 1-5 |
LTF | lactotransferrin |
MAGEA6 | melanoma antigen family A6 |
MALL | mal, T-cell differentiation protein-like |
MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |