Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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67 genes differentially expressed following the BRD-K94012289_OSI-027_PC3_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABHD2 | abhydrolase domain containing 2 |
ADGRG6 | adhesion G protein-coupled receptor G6 |
ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
APOD | apolipoprotein D |
ATP11B | ATPase, class VI, type 11B |
BEX1 | brain expressed, X-linked 1 |
CLDN3 | claudin 3 |
CTGF | connective tissue growth factor |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
DUSP4 | dual specificity phosphatase 4 |
GSN | gelsolin |
HIST1H2BG | histone cluster 1, H2bg |
HMGA2 | high mobility group AT-hook 2 |
IFI27 | interferon, alpha-inducible protein 27 |
IFIH1 | interferon induced with helicase C domain 1 |
KLK11 | kallikrein-related peptidase 11 |
KLK6 | kallikrein-related peptidase 6 |
LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
LTBP3 | latent transforming growth factor beta binding protein 3 |
MAGED1 | melanoma antigen family D1 |
MAOB | monoamine oxidase B |
MGP | matrix Gla protein |
MX1 | MX dynamin-like GTPase 1 |
MYOF | myoferlin |
NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
NET1 | neuroepithelial cell transforming 1 |
OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
PRUNE2 | prune homolog 2 (Drosophila) |
RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
RGS4 | regulator of G-protein signaling 4 |
RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
TRAPPC6A | trafficking protein particle complex 6A |
Symbol | Name |
---|---|
ADM | adrenomedullin |
BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
CA12 | carbonic anhydrase XII |
CHN1 | chimerin 1 |
CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
COL7A1 | collagen, type VII, alpha 1 |
CSTA | cystatin A (stefin A) |
CXCL3 | chemokine (C-X-C motif) ligand 3 |
CXCL5 | chemokine (C-X-C motif) ligand 5 |
CXCR4 | chemokine (C-X-C motif) receptor 4 |
DDIT4 | DNA-damage-inducible transcript 4 |
FADS1 | fatty acid desaturase 1 |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
KDM3A | lysine (K)-specific demethylase 3A |
KRT17 | keratin 17, type I |
MAGEA6 | melanoma antigen family A6 |
MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
ODC1 | ornithine decarboxylase 1 |
PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
S100A8 | S100 calcium binding protein A8 |
SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SNAI2 | snail family zinc finger 2 |
TFRC | transferrin receptor |
TRBC1 | T cell receptor beta constant 1 |
VEGFA | vascular endothelial growth factor A |
WNT5A | wingless-type MMTV integration site family, member 5A |